Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

Developmental origins of health and disease: current knowledge and potential mechanisms

DJ Hoffman, RM Reynolds, DB Hardy - Nutrition reviews, 2017 - academic.oup.com
Epidemiologic and clinical research has provided a large body of evidence supporting the
developmental origins of health and disease (DOHaD), but there has been a relative dearth …

Developmental origins of health and disease: the relevance to developing nations

M Mandy, M Nyirenda - International health, 2018 - academic.oup.com
Low-and middle-income countries (LMICs), particularly those in sub-Saharan Africa, are
experiencing rapid increases in the prevalence of non-communicable diseases (NCDs) …

[HTML][HTML] Metabolic syndrome: definitions and controversies

E Kassi, P Pervanidou, G Kaltsas, G Chrousos - BMC medicine, 2011 - Springer
Metabolic syndrome (MetS) is a complex disorder defined by a cluster of interconnected
factors that increase the risk of cardiovascular atherosclerotic diseases and diabetes …

From conception to infancy—early risk factors for childhood obesity

E Larqué, I Labayen, CE Flodmark, I Lissau… - Nature Reviews …, 2019 - nature.com
Maternal lifestyle during pregnancy, as well as early nutrition and the environment infants
are raised in, are considered relevant factors for the prevention of childhood obesity. Several …

Effect of in utero and early-life conditions on adult health and disease

PD Gluckman, MA Hanson, C Cooper… - New England journal …, 2008 - Mass Medical Soc
Many lines of evidence, including epidemiologic data and extensive clinical and
experimental studies, indicate that early life events play a powerful role in influencing later …

Ten putative contributors to the obesity epidemic

EJ McAllister, NV Dhurandhar, SW Keith… - Critical reviews in …, 2009 - Taylor & Francis
The obesity epidemic is a global issue and shows no signs of abating, while the cause of
this epidemic remains unclear. Marketing practices of energy-dense foods and institutionally …

[PDF][PDF] The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis

AM O'Carroll, SJ Lolait, LE Harris, GR Pope - J Endocrinol, 2013 - academia.edu
The apelin receptor (APJ; gene symbol APLNR) is a member of the G protein-coupled
receptor gene family. Neural gene expression patterns of APJ, and its cognate ligand apelin …

[HTML][HTML] Intrauterine programming of obesity and type 2 diabetes

DS Fernandez-Twinn, L Hjort, B Novakovic, SE Ozanne… - Diabetologia, 2019 - Springer
The type 2 diabetes epidemic and one of its predisposing factors, obesity, are major
influences on global health and economic burden. It is accepted that genetics and the …

Preterm birth and body composition at term equivalent age: a systematic review and meta-analysis

MJ Johnson, SA Wootton, AA Leaf, AA Jackson - Pediatrics, 2012 - publications.aap.org
BACKGROUND AND OBJECTIVE: Infants born preterm are significantly lighter and shorter
on reaching term equivalent age (TEA) than are those born at term, but the relation with …