The endothelium is recognized to play an important role in various physiological functions
including vascular tone, permeability, anticoagulation, and angiogenesis. Endothelial …

Sepsis, a medical emergency, is the overwhelming host response to infection leading to
organ failure. The pathophysiology of this heterogeneous disease includes an inflammatory …

Purpose Shock is a life-threatening condition characterized by substantial alterations in the
microcirculation. This study tests the hypothesis that considering sublingual microcirculatory …

The vascular endothelium is crucial for the maintenance of vascular homeostasis. Moreover,
in sepsis, endothelial cells can acquire new properties and actively participate in the host's …

Acute respiratory distress syndrome (ARDS) after cardiac surgery is reported with a widely
variable incidence (from 0.4%-8.1%). Cardiac surgery patients usually are affected by …

Purpose Severe sepsis and septic shock may impair microcirculatory perfusion and cause
organ dysfunction. The aim of this pilot study was to assess a new microcirculation-guided …

Circulatory failure in sepsis is common and places a considerable burden on healthcare
systems. It is associated with an increased likelihood of mortality, and timely recognition is a …

Endothelial integrity maintains microcirculatory flow and tissue oxygen delivery. The
endothelial glycocalyx is involved in cell signalling, coagulation and inflammation. Our …

It is evident that the admission of some patients with sepsis and septic shock to hospitals is
occurring late in their illness, which has contributed to the increase in poor outcomes and …

BACKGROUND: The incidence of postoperative microcirculatory flow alterations and their
effect on outcome have not been studied extensively. OBJECTIVE: This systematic review …