The Physiology of Enteric Glia
J Gonzales, BD Gulbransen - Annual Review of Physiology, 2024 - annualreviews.org
Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …
The role of neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance
M Echeverria-Villalobos, V Tortorici, BE Brito… - Frontiers in …, 2023 - frontiersin.org
Current evidence suggests that activation of glial and immune cells leads to increased
production of proinflammatory mediators, creating a neuroinflammatory state …
production of proinflammatory mediators, creating a neuroinflammatory state …
IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer
L van Baarle, V De Simone, L Schneider… - Nature …, 2024 - nature.com
Enteric glia have been recently recognized as key components of the colonic tumor
microenvironment indicating their potential role in colorectal cancer pathogenesis. Although …
microenvironment indicating their potential role in colorectal cancer pathogenesis. Although …
From diversity to disease: unravelling the role of enteric glial cells
Enteric glial cells (EGCs) are an essential component of the enteric nervous system (ENS)
and play key roles in gastrointestinal development, homeostasis, and disease. Derived from …
and play key roles in gastrointestinal development, homeostasis, and disease. Derived from …
Guardians of the gut: influence of the enteric nervous system on the intestinal epithelial barrier
The intestinal mucosal surface forms one of the largest areas of the body, which is in direct
contact with the environment. Co-ordinated sensory functions of immune, epithelial, and …
contact with the environment. Co-ordinated sensory functions of immune, epithelial, and …
β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery
P Leven, R Schneider, L Schneider, S Mallesh… - Journal of …, 2023 - Springer
Background Enteric glia contribute to the pathophysiology of various intestinal immune-
driven diseases, such as postoperative ileus (POI), a motility disorder and common …
driven diseases, such as postoperative ileus (POI), a motility disorder and common …
Down-regulation of ABCA7 in human microglia, astrocyte and THP-1 cell lines by cholesterol depletion, IL-1β and TNFα, or PMA
JP Wiener, S Desire, V Garliyev, N Lyssenko III… - Cells, 2023 - mdpi.com
Adenosine triphosphate-binding cassette transporter subfamily A member 7 (ABCA7) is a
major risk factor for Alzheimer's disease. Human neural cell lines were used to investigate …
major risk factor for Alzheimer's disease. Human neural cell lines were used to investigate …
BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus
E Mazzotta, I Grants… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose ET‐1 signalling modulates intestinal motility and inflammation, but
the role of ET‐1/ETB receptor signalling is poorly understood. Enteric glia modulate normal …
the role of ET‐1/ETB receptor signalling is poorly understood. Enteric glia modulate normal …
Enteric neuro-immune interactions in intestinal health and disease
L van Baarle, M Stakenborg, G Matteoli - Seminars in Immunology, 2023 - Elsevier
The enteric nervous system is an autonomous neuronal circuit that regulates many
processes far beyond the peristalsis in the gastro-intestinal tract. This circuit, consisting of …
processes far beyond the peristalsis in the gastro-intestinal tract. This circuit, consisting of …
Mini-Review: Enteric Glial Cell Reactions to Inflammation and Potential Therapeutic Implications for GI Diseases, Motility Disorders and Abdominal Pain
A Linan-Rico, F Ochoa-Cortes, R Schneider… - Neuroscience …, 2023 - Elsevier
Enteric glial cells are emerging as critical players in the regulation of intestinal motility,
secretion, epithelial barrier function, and gut homeostasis in health and disease. Enteric glia …
secretion, epithelial barrier function, and gut homeostasis in health and disease. Enteric glia …