Differentiation of hematopoietic cells involves progressive restriction of developmental
potential as pluripotent hematopoietic stem cells give rise to multipoten-tial progenitors that …

The differentiation of naive CD4+ T cells into subsets of T helper cells is a pivotal process
with major implications for host defense and the pathogenesis of immune-mediated …

GATA-binding proteins constitute a family of transcription factors that recognize a target site
conforming to the consensus WGATAR (W= A or T and R= A or G). Here we have used the …

We report the cDNA cloning and characterization of mouse GATA-4, a new member of the
family of zinc finger transcription factors that bind a core GATA motif. GATA-4 cDNA was …

Members of the GATA family of transcription factors, which are related by a high degree of
amino acid sequence identity within their zinc finger DNA-binding domains, each show …

GATA–3 is one member of a growing family of related transcription factors which share a
strongly conserved expression pattern in all vertebrate organisms. In order to elucidate …

Vascular cell adhesion molecule-1 (VCAM-1) was first identified as a protein that appears on
the surface of endothelial cells after exposure to inflammatory cytokines. Through interaction …

The GATA-binding transcription factors comprise a protein family whose members contain
either one or two highly conserved zinc finger DNA-binding domains. Members of this group …

The discovery of the GATA binding protein (GATA factor) transcription factor family
revolutionized hematology. Studies of GATA proteins have yielded vital contributions to our …

Mouse embryonic stem (ES) cells lacking the transcription factor GATA-1 do not produce
mature red blood cells either in vivo or in vitro. To define the consequences of GATA-1 loss …