[HTML][HTML] Antimicrobial resistance acquisition via natural transformation: context is everything

M Winter, A Buckling, K Harms, PJ Johnsen… - Current Opinion in …, 2021 - Elsevier
Highlights•Natural transformation mediates the spread of antibiotic resistance
genes.•Natural transformation can aid gene transfer between unrelated taxa.•Natural …

Rates of lateral gene transfer in prokaryotes: high but why?

M Vos, MC Hesselman, TA Te Beek… - Trends in …, 2015 - cell.com
Lateral gene transfer is of fundamental importance to the evolution of prokaryote genomes
and has important practical consequences, as evidenced by the rapid dissemination of …

Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation

S Fulsundar, K Harms, GE Flaten… - Applied and …, 2014 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are continually released from a range of bacterial species.
Numerous functions of OMVs, including the facilitation of horizontal gene transfer (HGT) …

Directed networks reveal genomic barriers and DNA repair bypasses to lateral gene transfer among prokaryotes

O Popa, E Hazkani-Covo, G Landan, W Martin… - Genome …, 2011 - genome.cshlp.org
Lateral gene transfer (LGT) plays a major role in prokaryote evolution with only a few genes
that are resistant to it; yet the nature and magnitude of barriers to lateral transfer are still …

Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species

S Domingues, K Harms, WF Fricke, PJ Johnsen… - 2012 - journals.plos.org
We have investigated to what extent natural transformation acting on free DNA substrates
can facilitate transfer of mobile elements including transposons, integrons and/or gene …

DNA modifications impact natural transformation of Acinetobacter baumannii

N Vesel, C Iseli, N Guex, A Lemopoulos… - Nucleic Acids …, 2023 - academic.oup.com
Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability
to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A …

Cell-free DNA: an underestimated source of antibiotic resistance gene dissemination at the interface between human activities and downstream environments in the …

M Woegerbauer, X Bellanger, C Merlin - Frontiers in Microbiology, 2020 - frontiersin.org
The dissemination of antimicrobial resistance (AMR) is one of the biggest challenges faced
by mankind in the public health domains. It is currently favored by a lack of confinement …

The stability and degradation of dietary DNA in the gastrointestinal tract of mammals: implications for horizontal gene transfer and the biosafety of GMOs

A Rizzi, N Raddadi, C Sorlini, L Nordgrd… - Critical Reviews in …, 2012 - Taylor & Francis
The fate of dietary DNA in the gastrointestinal tract (GIT) of animals has gained renewed
interest after the commercial introduction of genetically modified organisms (GMO). Among …

Fitness costs of various mobile genetic elements in Enterococcus faecium and Enterococcus faecalis

I Starikova, M Al-Haroni, G Werner… - Journal of …, 2013 - academic.oup.com
Objectives To determine the fitness effects of various mobile genetic elements (MGEs) in
Enterococcus faecium and Enterococcus faecalis when newly acquired. We also tested the …

Competence for Natural Transformation Is Common among Clinical Strains of Resistant Acinetobacter spp.

S Domingues, N Rosário, Â Cândido, D Neto… - Microorganisms, 2019 - mdpi.com
Horizontal gene transfer events provide the basis for extensive dissemination of
antimicrobial resistance traits between bacterial populations. Conjugation is considered to …