Wound healing is a multistep process with four overlapping but distinct stages: hemostasis,
inflammation, proliferation, and remodeling. An alteration at any stage may lead to the …

Normal wound healing occurs through a careful orchestration of cytokine and chemokine
signaling in response to injury. Chemokines are a small family of chemotactic cytokines that …

Adipose stem cells (ASCs) have attracted considerable attention as potential therapeutic
agents due to their ability to promote tissue regeneration. However, their limited tissue repair …

Ticks secrete various anti-coagulatory, anti-vasoconstrictory, anti-inflammatory, and anti-
platelet aggregation factors in their saliva at the bite site during feeding to evade host …

Molecular effects of various ablative and non-ablative laser treatments on human skin cells—
especially primary effects on epidermal keratinocytes and dermal fibroblasts—are not yet …

Chronic skin wounds are a common complication of diabetes. When standard wound care
fails to heal such wounds, a promising approach consists of using decellularized matrices …

Objectives: We have previously shown that stromal cell–derived factor-1α (SDF-1α) is
downregulated within diabetic cutaneous wounds, and that direct application of recombinant …

Significance: Impaired wound healing leading to chronic wounds is an important clinical
problem that needs immediate attention to develop new effective therapies. Members of the …

Migration of cells from both local and systemic sources is essential for the inflammatory and
regenerative processes that occur during normal wound healing. CXCL12 is considered a …

Background Non-healing wounds are a major global health concern and account for the
majority of non-traumatic limb amputations worldwide. However, compared to standard care …