Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery

B Prevo, JM Scholey, EJG Peterman - The FEBS journal, 2017 - Wiley Online Library
Intraflagellar transport (IFT) is a form of motor‐dependent cargo transport that is essential for
the assembly, maintenance, and length control of cilia, which play critical roles in motility …

Intraflagellar transport and ciliary dynamics

H Ishikawa, WF Marshall - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Cilia and flagella are microtubule-based organelles whose assembly requires a motile
process, known as intraflagellar transport (IFT), to bring tubulin and other components to the …

[图书][B] Stochastic processes in cell biology

PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

[HTML][HTML] Dynamics of the IFT machinery at the ciliary tip

A Chien, SM Shih, R Bower, D Tritschler, ME Porter… - Elife, 2017 - elifesciences.org
Intraflagellar transport (IFT) is essential for the elongation and maintenance of eukaryotic
cilia and flagella. Due to the traffic jam of multiple trains at the ciliary tip, how IFT trains are …

[HTML][HTML] Assembly, functions and evolution of archaella, flagella and cilia

S Khan, JM Scholey - Current Biology, 2018 - cell.com
Cells from all three domains of life on Earth utilize motile macromolecular devices that
protrude from the cell surface to generate forces that allow them to swim through fluid media …

Scaling of subcellular structures

WF Marshall - Annual review of cell and developmental biology, 2020 - annualreviews.org
As cells grow, the size and number of their internal organelles increase in order to keep up
with increased metabolic requirements. Abnormal size of organelles is a hallmark of cancer …

Motor cooperation during mitosis and ciliogenesis

G Ou, JM Scholey - Annual Review of Cell and Developmental …, 2022 - annualreviews.org
Cilia and mitotic spindles are microtubule (MT)-based, macromolecular machines that
consecutively assemble and disassemble during interphase and M phase of the cell cycle …

[HTML][HTML] Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium

JN Hansen, F Kaiser, C Klausen, B Stüven, R Chong… - Elife, 2020 - elifesciences.org
Compartmentalization of cellular signaling forms the molecular basis of cellular behavior.
The primary cilium constitutes a subcellular compartment that orchestrates signal …

Cell geometry: how cells count and measure size

WF Marshall - Annual review of biophysics, 2016 - annualreviews.org
The cell represents a highly organized state of living matter in which numerous geometrical
parameters are under dynamic regulation in order to match the form of a cell with its function …

[HTML][HTML] Diffusion as a ruler: modeling kinesin diffusion as a length sensor for intraflagellar transport

NL Hendel, M Thomson, WF Marshall - Biophysical journal, 2018 - cell.com
An important question in cell biology is whether cells are able to measure size, either whole
cell size or organelle size. Perhaps cells have an internal chemical representation of size …