The impact of HIV-1 within-host evolution on transmission dynamics

K Theys, P Libin, AC Pineda-Pena, A Nowe… - Current opinion in …, 2018 - Elsevier
Highlights•HIV-1 within-host evolution is short-sighted and favours more virulent
viruses.•Systemic HIV-1 infection is mainly established by a single variant …

Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure

S Avila-Rios, JM Carlson, M John, S Mallal… - Current Opinion in …, 2019 - journals.lww.com
Clinical and evolutionary consequences of HIV adaptation to... : Current Opinion in HIV and
AIDS Clinical and evolutionary consequences of HIV adaptation to HLA: implications for …

Extensive host immune adaptation in a concentrated North American HIV epidemic

ZL Brumme, NN Kinloch, S Sanche, A Wong, E Martin… - Aids, 2018 - journals.lww.com
Objective: HIV incidence in the Canadian province of Saskatchewan, where Indigenous
persons make up 80% of those infected, are among the highest on the continent. Reports of …

Evidence for a recombinant origin of HIV-1 Group M from genomic variation

AS Olabode, M Avino, GT Ng, F Abu-Sardanah… - Virus …, 2019 - academic.oup.com
Reconstructing the early dynamics of the HIV-1 pandemic can provide crucial insights into
the socioeconomic drivers of emerging infectious diseases in human populations, including …

[PDF][PDF] HIV-1 p24Gag adaptation to modern and archaic HLA-allele frequency differences in ethnic groups contributes to viral subtype diversification

NC Kist, B Lambert, S Campbell, A Katzourakis… - Virus …, 2020 - academic.oup.com
Pathogen-driven selection and past interbreeding with archaic human lineages have
resulted in differences in human leukocyte antigen (HLA)-allele frequencies between …

HIV-1 subtype diversity, phylogenetic analysis and study of drug resistance in strains circulating in the Ural Federal District

MV Piterskiy, AG Gusev, OA Khodakov… - Journal of …, 2022 - microbiol.crie.ru
Abstract Introduction. Ural Federal District (UFD) has been one of the most HIV-affected
areas in the Russian Federation during past 20 years. The total number of people living with …

Weaker HLA footprints on HIV in the unique and highly genetically admixed host population of Mexico

M Soto-Nava, S Avila-Rios… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT HIV circumvents HLA class I-restricted CD8+ T-cell responses through selection
of escape mutations that leave characteristic mutational “footprints,” also known as HLA …

T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics

T Akahoshi, H Gatanaga, N Kuse, T Chikata… - PLoS …, 2020 - journals.plos.org
HIV-1 strains harboring immune escape mutations can persist in circulation, but the impact
of selection by multiple HLA alleles on population HIV-1 dynamics remains unclear. In …

[HTML][HTML] Разнообразие субтипов, филогенетический анализ и изучение лекарственной устойчивости штаммов ВИЧ-1, циркулирующих в Уральском …

МВ Питерский, АГ Гусев, ОА Ходаков… - Журнал …, 2022 - cyberleninka.ru
Введение. Уральский федеральный округ (УФО) является одной из наиболее
эпидемически неблагополучных территорий в Российской Федерации по ВИЧ …

Genetic divergence of HIV-1 B subtype in Italy over the years 2003–2016 and impact on CTL escape prevalence

C Alteri, L Fabeni, R Scutari, G Berno, D Di Carlo… - Scientific Reports, 2018 - nature.com
HIV-1 is characterized by high genetic variability, with implications for spread, and immune-
escape selection. Here, the genetic modification of HIV-1 B subtype over time was evaluated …