[PDF][PDF] Concise review: gamma-glutamyl transferase-evolution from an indiscriminate liver test to a biomarker of cardiometabolic risk

A Lonardo, G Ndrepepa - Metab Target Organ Damage, 2022 - f.oaes.cc
This concise review article critically examines the recent medical literature regarding gamma
glutamyl transferase (GGT) with a special emphasis on newly proposed indications for GGT …

Acacetin inhibited non-small-cell lung cancer (NSCLC) cell growth via upregulating miR-34a in vitro and in vivo

J Li, X Zhong, Y Zhao, J Shen, Z Xiao, C Pilapong - Scientific Reports, 2024 - nature.com
Acacetin, one of the flavonoid compounds, is a natural product found in various plants,
including Silver birch, and Damiana. Previous studies showed that acacetin has anti-cancer …

Liver-related aspects of valoctocogene roxaparvovec gene therapy for hemophilia A: expert guidance for clinical practice

V La Mura, V Cardinale, R De Cristofaro… - Blood …, 2024 - ashpublications.org
Adeno-associated virus–based gene therapy (valoctocogene roxaparvovec) is an attractive
treatment for hemophilia A. Careful clinical management is required to minimize the risk of …

Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review

KW Foong, SH Chaw, YL Lo, PS Loh - Clinical Pharmacokinetics, 2024 - Springer
Background The establishment of optimal dosing regimens for intravenous (IV) lidocaine in
the perioperative setting, aiming to balance effective pain relief with minimisation of potential …

[HTML][HTML] A new nano approach to prevent tumor growth in the local treatment of glioblastoma: Temozolomide and rutin-loaded hybrid layered composite nanofiber

M Ercelik, C Tekin, M Gurbuz, Y Tuncbilekli… - Asian Journal of …, 2024 - Elsevier
Total resection of glioblastoma (GB) tumors is nearly impossible, and systemic
administration of temozolomide (TMZ) is often inadequate. This study presents a hybrid …

Comparative Proteomic Analysis of Liver Tissues and Serum in db/db Mice

Y Zhang, X Wu, M Xu, T Yue, P Ling, T Fang… - International Journal of …, 2022 - mdpi.com
Background and Aims: Non-alcoholic fatty liver disease (NAFLD) affects one-quarter of
individuals worldwide. Liver biopsy, as the current reliable method for NAFLD evaluation …

The Effect of Mesenchymal Stem Cell‐Derived Exosomes and miR17‐5p Inhibitor on Multicellular Liver Fibrosis Microtissues

F Sani, M Soufi Zomorrod, N Azarpira… - Stem Cells …, 2023 - Wiley Online Library
Background. Although several studies have been conducted on modeling human liver
disease, it is still challenging to mimic nonalcoholic fatty liver disease in vitro. Here, we …

The relationship between homoarginine and liver biomarkers: a combination of epidemiological and clinical studies

A Aghdassi, E Schwedhelm, D Atzler, M Nauck… - Scientific Reports, 2023 - nature.com
Homoarginine (hArg) is a non-essential cationic amino acid which inhibits hepatic alkaline
phosphatases to exert inhibitory effects on bile secretion by targeting intrahepatic biliary …

Prevalence and association of hyperuricemia with liver function in Saudi Arabia: a large cross-sectional study

A Almuqrin, YA Alshuweishi, M Alfaifi… - Annals of Saudi …, 2024 - annsaudimed.net
BACKGROUND: Hyperuricemia is linked to an increased risk of various chronic diseases,
but data on the prevalence and association of hyperuricemia with liver function in Saudi …

Echinocystic acid inhibits sepsis-associated renal inflammation and apoptosis by targeting protein tyrosine phosphatase 1B

D Wu, H Li, L Wang, Y Hu, H Huang, J Li… - International …, 2024 - Elsevier
The fruits of Gleditsia sinensis Lam. have been utilized to treat inflammatory diseases in
China. Echinocystic acid (EA), one pentacyclic triterpenoid isolated from the fruits of G …