Biology and biomechanics of the heart valve extracellular matrix
KM Kodigepalli, K Thatcher, T West… - Journal of …, 2020 - mdpi.com
Heart valves are dynamic structures that, in the average human, open and close over
100,000 times per day, and 3× 109 times per lifetime to maintain unidirectional blood flow …
100,000 times per day, and 3× 109 times per lifetime to maintain unidirectional blood flow …
Mechanical considerations for polymeric heart valve development: Biomechanics, materials, design and manufacturing
The native human heart valve leaflet contains a layered microstructure comprising a
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …
hierarchical arrangement of collagen, elastin, proteoglycans and various cell types. Here …
Computational methods for the aortic heart valve and its replacements
Introduction: Replacement with a prosthetic device remains a major treatment option for the
patients suffering from heart valve disease, with prevalence growing resulting from an …
patients suffering from heart valve disease, with prevalence growing resulting from an …
Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves
EL Johnson, DW Laurence, F Xu, CE Crisp… - Computer methods in …, 2021 - Elsevier
Approximately 1.6 million patients in the United States are affected by tricuspid valve
regurgitation, which occurs when the tricuspid valve does not close properly to prevent …
regurgitation, which occurs when the tricuspid valve does not close properly to prevent …
Mechanical experimentation of the gastrointestinal tract: a systematic review
The gastrointestinal (GI) organs of the human body are responsible for transporting and
extracting nutrients from food and drink, as well as excreting solid waste. Biomechanical …
extracting nutrients from food and drink, as well as excreting solid waste. Biomechanical …
Patient-specific inverse modeling of in vivo cardiovascular mechanics with medical image-derived kinematics as input data: concepts, methods, and applications
JH Bracamonte, SK Saunders, JS Wilson, UT Truong… - Applied Sciences, 2022 - mdpi.com
Inverse modeling approaches in cardiovascular medicine are a collection of methodologies
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …
A noninvasive method for the determination of in vivo mitral valve leaflet strains
Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
Characterization of the layer, direction and time-dependent mechanical behaviour of the human oesophagus and the effects of formalin preservation
The mechanical characterization of the oesophagus is essential for applications such as
medical device design, surgical simulations and tissue engineering, as well as for …
medical device design, surgical simulations and tissue engineering, as well as for …
The effects of viscoelasticity on residual strain in aortic soft tissues
Residual stress is thought to play a critical role in modulating stress distributions in soft
biological tissues and in maintaining the mechanobiological stress environment of cells …
biological tissues and in maintaining the mechanobiological stress environment of cells …
A functionally graded material model for the transmural stress distribution of the aortic valve leaflet
Heterogeneities in structure and stress within heart valve leaflets are of significant concern
to their functional physiology, as they affect how the tissue constituents remodel in response …
to their functional physiology, as they affect how the tissue constituents remodel in response …