Supervised machine learning for population genetics: a new paradigm

DR Schrider, AD Kern - Trends in Genetics, 2018 - cell.com
As population genomic datasets grow in size, researchers are faced with the daunting task
of making sense of a flood of information. To keep pace with this explosion of data …

Approximate bayesian computation

MA Beaumont - Annual review of statistics and its application, 2019 - annualreviews.org
Many of the statistical models that could provide an accurate, interesting, and testable
explanation for the structure of a data set turn out to have intractable likelihood functions …

Efficient ancestry and mutation simulation with msprime 1.0

F Baumdicker, G Bisschop, D Goldstein, G Gower… - Genetics, 2022 - academic.oup.com
Stochastic simulation is a key tool in population genetics, since the models involved are
often analytically intractable and simulation is usually the only way of obtaining ground-truth …

[图书][B] Handbook of approximate Bayesian computation

SA Sisson, Y Fan, M Beaumont - 2018 - books.google.com
As the world becomes increasingly complex, so do the statistical models required to analyse
the challenging problems ahead. For the very first time in a single volume, the Handbook of …

Benchmarking simulation-based inference

JM Lueckmann, J Boelts, D Greenberg… - International …, 2021 - proceedings.mlr.press
Recent advances in probabilistic modelling have led to a large number of simulation-based
inference algorithms which do not require numerical evaluation of likelihoods. However, a …

Automatic posterior transformation for likelihood-free inference

D Greenberg, M Nonnenmacher… - … on Machine Learning, 2019 - proceedings.mlr.press
How can one perform Bayesian inference on stochastic simulators with intractable
likelihoods? A recent approach is to learn the posterior from adaptively proposed …

Sequential neural likelihood: Fast likelihood-free inference with autoregressive flows

G Papamakarios, D Sterratt… - The 22nd international …, 2019 - proceedings.mlr.press
Abstract We present Sequential Neural Likelihood (SNL), a new method for Bayesian
inference in simulator models, where the likelihood is intractable but simulating data from …

Training deep neural density estimators to identify mechanistic models of neural dynamics

PJ Gonçalves, JM Lueckmann, M Deistler… - Elife, 2020 - elifesciences.org
Mechanistic modeling in neuroscience aims to explain observed phenomena in terms of
underlying causes. However, determining which model parameters agree with complex and …

Approximate bayesian computation

M Sunnåker, AG Busetto, E Numminen… - PLoS computational …, 2013 - journals.plos.org
Approximate Bayesian computation (ABC) constitutes a class of computational methods
rooted in Bayesian statistics. In all model-based statistical inference, the likelihood function …

Flexible statistical inference for mechanistic models of neural dynamics

JM Lueckmann, PJ Goncalves… - Advances in neural …, 2017 - proceedings.neurips.cc
Mechanistic models of single-neuron dynamics have been extensively studied in
computational neuroscience. However, identifying which models can quantitatively …