Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

The term cirrhosis-associated immune dysfunction refers to the main syndromic
abnormalities of immune function, immunodeficiency and systemic inflammation that are …

Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

IgG glycosylation is currently at the forefront of both immunology and glycobiology, likely due
in part to the widespread and growing use of antibodies as drugs. For over four decades, it …

A loss of humoral tolerance is a hallmark of many autoimmune diseases and the detection of
self-reactive antibodies (autoantibodies) of the immunoglobulin G (IgG) isotype is widely …

A multitude of monoclonal IgG antibodies directed against a variety of therapeutic targets is
currently being developed and produced by biotechnological companies. The biological …

Glycosylation is a frequent co/post-translational modification of proteins which modulates a
variety of biological functions. The analysis of N-glycome, ie the sugar chains N-linked to …

Background & Aims: Human immunodeficiency virus (HIV)-1 infection has been associated
with enhanced microbial translocation, and microbial translocation is a mechanism through …

Chronic liver diseases are a serious health problem worldwide. The current gold standard to
assess structural liver damage is through a liver biopsy which has several disadvantages. A …

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and
the cancer with the fastest increase in mortality in the United States, with more than 39,000 …