Colorectal cancer in ulcerative colitis: mechanisms, surveillance and chemoprevention

W Li, T Zhao, D Wu, J Li, M Wang, Y Sun, S Hou - Current Oncology, 2022 - mdpi.com
Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

Gut microbiota and colorectal cancer development: a closer look to the adenoma-carcinoma sequence

M Vacante, R Ciuni, F Basile, A Biondi - Biomedicines, 2020 - mdpi.com
There is wide evidence that CRC could be prevented by regular physical activity, keeping a
healthy body weight, and following a healthy and balanced diet. Many sporadic CRCs …

Gut microbiota modulation: a tool for the management of colorectal cancer

Y Wang, H Li - Journal of Translational Medicine, 2022 - Springer
Colorectal cancer (CRC) is the second cause of cancer death and the third most frequently
diagnosed cancer. Besides the lifestyle, genetic and epigenetic alterations, and …

Gut Microbiota as Potential Biomarker and/or Therapeutic Target to Improve the Management of Cancer: Focus on Colibactin-Producing Escherichia coli in Colorectal …

J Veziant, R Villéger, N Barnich, M Bonnet - Cancers, 2021 - mdpi.com
Simple Summary Gut microbiota is emerging as new diagnostic and prognostic marker
and/or therapeutic target to improve the management of cancer. This review aims to …

Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer

M Oliero, R Hajjar, T Cuisiniere, G Fragoso, A Calvé… - Gut Pathogens, 2022 - Springer
Background Colorectal cancer (CRC) is the third most diagnosed cancer and the second
most common cause of cancer deaths worldwide. CRC patients present with an increase in …

Could microplastics be a driver for early onset colorectal cancer?

S Li, JI Keenan, IC Shaw, FA Frizelle - Cancers, 2023 - mdpi.com
Simple Summary The incidence of colorectal cancer has increasing dramatically in those
under 50 years of age. These cancers are prominently in the sigmoid colon and rectum. This …

Relationship between gut microbiota and colorectal cancer: Probiotics as a potential strategy for prevention

SY Lee, JH Kang, JH Kim, JW Jeong, HW Kim… - Food Research …, 2022 - Elsevier
Gut microbiota comprise microorganisms residing in the gastrointestinal tract. Some of these
microbiota are implicated in the progression of colorectal cancer (CRC). Here, we highlight …

Intratumoral presence of the genotoxic gut bacteria pks+E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with …

JE Joo, YL Chu, P Georgeson, R Walker… - British Journal of …, 2024 - nature.com
Background This study aimed to investigate clinicopathological and molecular tumour
features associated with intratumoral pks+ Escherichia coli (pks+ E. coli+), pks+ E. coli-(non …

Colorectal cancer: the facts in the case of the microbiota

SL Clay, D Fonseca-Pereira… - The Journal of clinical …, 2022 - Am Soc Clin Investig
The importance of the microbiota in the development of colorectal cancer (CRC) is
increasingly evident, but identifying specific microbial features that influence CRC initiation …

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

M Oliero, A Calvé, G Fragoso, T Cuisiniere, R Hajjar… - BMC cancer, 2021 - Springer
Background Colibactin is a genotoxin that induces DNA double-strand breaks that may lead
to carcinogenesis and is produced by Escherichia coli strains harboring the pks island …