The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

The plasma membrane allows the cell to sense and adapt to changes in the extracellular
environment by relaying external inputs via intracellular signaling networks. One central …

Extracellular vesicles (EVs) are potential alternatives for mesenchymal stem cells (MSCs) in
the treatment of musculoskeletal degenerative diseases, including intervertebral disc …

Caveolae are submicroscopic, plasma membrane pits that are abundant in many
mammalian cell types. The past few years have seen a quantum leap in our understanding …

Curving biological membranes establishes the complex architecture of the cell and mediates
membrane traffic to control flux through subcellular compartments. Common molecular …

The functions of caveolae, the characteristic plasma membrane invaginations, remain
debated. Their abundance in cells experiencing mechanical stress led us to investigate their …

Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …

Caveolae are an abundant feature of the plasma membrane in many cells. Until recently,
they were generally considered to be membrane invaginations whose formation primarily …

Secretion of pulmonary surfactant in the alveoli of the lungs is essential to maintain lung
function. Stretching of alveoli during lung inflation is the main trigger for surfactant secretion …