Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

The outbreak of COVID-19, the pandemic disease caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spurred an intense search for treatments by the …

Depending on the inflammatory milieu, injury can result either in a tissue's complete
regeneration or in its degeneration and fibrosis, the latter of which could potentially lead to …

Platelet-derived growth factors (PDGF) promotes cell proliferation, survival and migration,
primarily of cells of mesenchymal origin. Dysfunction of PDGF signaling has been observed …

Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

The platelet‑derived growth factor (PDFG) signaling pathway exerts persistent activation in
response to a variety of stimuli and facilitates the progression of hepatic fibrosis. Since this …

Fibrosis, which leads to progressive loss of tissue function and eventual organ failure, has
been estimated to contribute to~ 45% of deaths in the developed world, and so new …

Platelet-derived growth factor (PDGF) was discovered as a serum-derived component
necessary for the growth of smooth muscle cells, fibroblasts, and glial cells. The PDGF family …

Platelet derived growth factor (PDGF) signaling plays an important role in activated hepatic
stellate cells and portal fibroblast proliferation, chemotaxis, migration and cell survival …

Platelet‐derived growth factor (PDGF) isoforms and their receptors have important roles
during embryogenesis, particularly in the development of various mesenchymal cell types in …