After more than two decades of rising rates, in recent years the total kidney cancer incidence
worldwide has shown signs of stabilizing, or even decreasing. In adults, kidney cancer …

Trichloroethylene (TCE) is a suspected renal carcinogen. TCE-associated renal genotoxicity
occurs predominantly through glutathione S-transferase (GST) conjugation and bioactivation …

Aim: Identifying high-efficiency prognostic markers for colorectal cancer (CRC) is necessary
for clinical practice. Increasing evidence demonstrates that apolipoprotein C1 (APOC1) …

Renal cell carcinoma (RCC) comprises a heterogeneous group of histologically and
molecularly distinct tumour subtypes. Current targeted therapies have improved survival in …

Background. Thyroid cancer is the most common endocrine malignancy, with a recent global
increase of 20% in age‐related incidence. Ultrasonography and ultrasonography‐guided …

Background Germline genetic polymorphisms might affect the risk of recurrence in patients
with localised renal-cell carcinoma. We investigated the association between genetic …

Abstract Background Apolipoprotein E (ApoE) is a multifunctional protein playing both a key
role in the metabolism of cholesterol and triglycerides, and in tissue repair and inflammation …

Pancreatic cancer (PC) remains a devastating disease with a five‑year survival rate of< 5%.
The difficulty in making an early diagnosis and the frequent occurrence of metastasis are …

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• SLCO1B3 is an influx transporter
located at the hepatocyte basolateral membrane and it is involved in the uptake of a broad …

In follow-up of a recent genome-wide association study (GWAS) that identified a locus in
chromosome 2p21 associated with risk for renal cell carcinoma (RCC), we conducted a fine …