[HTML][HTML] Cellular mechanisms of cooperative context-sensitive predictive inference

T Marvan, WA Phillips - Current Research in Neurobiology, 2024 - Elsevier
We argue that prediction success maximization is a basic objective of cognition and cortex,
that it is compatible with but distinct from prediction error minimization, that neither objective …

[HTML][HTML] Dysfunctions of cellular context-sensitivity in neurodevelopmental learning disabilities

A Granato, WA Phillips, JM Schulz, M Suzuki… - Neuroscience & …, 2024 - Elsevier
Pyramidal neurons have a pivotal role in the cognitive capabilities of neocortex. Though they
have been predominantly modeled as integrate-and-fire point processors, many of them …

[HTML][HTML] Layer 1 NDNF interneurons are specialized top-down master regulators of cortical circuits

J Hartung, A Schroeder, RAP Vázquez, RB Poorthuis… - Cell Reports, 2024 - cell.com
Diverse types of inhibitory interneurons (INs) impart computational power and flexibility to
neocortical circuits. Whereas markers for different IN types in cortical layers 2–6 (L2–L6) …

[HTML][HTML] A comparison of partial information decompositions using data from real and simulated layer 5b pyramidal cells

JW Kay, JM Schulz, WA Phillips - Entropy, 2022 - mdpi.com
Partial information decomposition allows the joint mutual information between an output and
a set of inputs to be divided into components that are synergistic or shared or unique to each …

[HTML][HTML] Preassembly of specific Gβγ subunits at GABAB receptors through auxiliary KCTD proteins accelerates channel gating

T Fritzius, R Tureček, D Fernandez-Fernandez… - Biochemical …, 2024 - Elsevier
GABA B receptors (GBRs) are G protein-coupled receptors for GABA, the main inhibitory
neurotransmitter in the brain. GBRs regulate fast synaptic transmission by gating Ca 2+ and …

Partial information decomposition for continuous variables based on shared exclusions: Analytical formulation and estimation

DA Ehrlich, K Schick-Poland, A Makkeh, F Lanfermann… - Physical Review E, 2024 - APS
Describing statistical dependencies is foundational to empirical scientific research. For
uncovering intricate and possibly nonlinear dependencies between a single target variable …

Cell-Type–Specific Effects of Somatostatin on Synaptic Transmission in the Anterior Cingulate Cortex

T Riedemann, B Sutor - Journal of Neuroscience, 2024 - Soc Neuroscience
Inhibitory modulation of glutamatergic information processing is a prerequisite for proper
network function. Among the many groups of interneurons (INs), somatostatin-expressing …

Context-sensitive neocortical neurons transform the effectiveness and efficiency of neural information processing

A Adeel, M Franco, M Raza, K Ahmed - arXiv preprint arXiv:2207.07338, 2022 - arxiv.org
Deep learning (DL) has big-data processing capabilities that are as good, or even better,
than those of humans in many real-world domains, but at the cost of high energy …

[HTML][HTML] Chemogenetic silencing of differentiating cortical neurons impairs dendritic and axonal growth

I Gasterstädt, M Schröder, L Cronin, J Kusch… - Frontiers in Cellular …, 2022 - frontiersin.org
Electrical activity is considered a key driver for the neurochemical and morphological
maturation of neurons and the formation of neuronal networks. Designer receptors …

A Partial Information Decomposition for Multivariate Gaussian Systems Based on Information Geometry

JW Kay - Entropy, 2024 - mdpi.com
There is much interest in the topic of partial information decomposition, both in developing
new algorithms and in developing applications. An algorithm, based on standard results …