Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Abstract β-Hydroxybutyrate (βOHB), a ketone body, is oxidised as a brain fuel. Although its
contribution to energy metabolism in the healthy brain is minimal, it is an interesting …

Cisplatin, as a commonly used anticancer drug, can easily lead to acute kidney injury (AKI),
and has received more and more attention in clinical practice. β-hydroxybutyric acid (BHB) is …

Mitochondrial activity and quality control are essential for neuronal homeostasis as neurons
rely on glucose oxidative metabolism. The ketone body, D-β-hydroxybutyrate (D-BHB), is …

Nutrition and rehabilitation are crucial in post-stroke recovery, especially in the elderly.
Since stroke is the leading cause of long-term disability, there is a need to promote special …

The ketogenic diet (KD), a diet high in fat and protein but low in carbohydrates, is gaining
much interest due to its positive effects, especially in neurodegenerative diseases. Beta …

Background: The ketogenic diet (KD) has become widespread for the therapy of epileptic
pathology in childhood and adulthood. In the last few decades, the current re-emergence of …

The ketone metabolite β-hydroxybutyrate (βOHB), is reported to be neuroprotective after
spinal cord injury (SCI) in rats, but the underlying mechanism remains unknown. The …

Background: Accumulation of amyloid β (Aβ) peptide, inflammation, and oxidative stress
contribute to Alzheimer's disease (AD) and trigger complex pathogenesis. The ketone body …

Headaches are among the most prevalent and disabling neurologic disorders and there are
several unmet needs as current pharmacological options are inadequate in treating patients …