IgG4 related disease was recognized as a unified disease entity only 15 years ago.
Awareness of IgG4 related disease has increased worldwide since then, and specialists are …

The extracellular forms of the IL‐1 cytokines are active through binding to specific receptors
on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand …

Background Although the mechanisms underlying AD neurodegeneration are not fully
understood, it is now recognised that inflammation could play a crucial role in the initiation …

ABSTRACT Introduction Awareness of IgG4-related disease (IgG4-RD) is increasing
worldwide and specialists are now familiar with most of its clinical manifestations and …

IgG4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease frequently
associated with allergy. The pathogenesis of IgG4-RD is poorly understood, and effective …

The pleiotropic cytokine IL-1 mediates its biological functions via association with the
signaling receptor IL-1R1. Despite an apparent simplicity in IL-1 signaling activation …

Abstract IgG4-related disease (IgG4-RD) has complex clinical manifestations ranging from
fibrosis and inflammation to deregulated metabolism. The molecular mechanisms …

ABSTRACT Introduction: IgG4-related disease (IgG4-RD) is an emerging systemic
inflammatory disease involving nearly all organs eventually leading to fibrosis. Prompt and …

Background. IgG4‐related disease (IgG4‐RD) is a fibroinflammatory condition. T‐cells play
a crucial role in the pathogenesis, and therefore, serum soluble interleukin‐2 receptor (sIL …

Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a chronic, clinically heterogenous
fibroinflammatory condition, characterised by an accumulation of IgG4 secreting plasma …