Ageing leads to dramatic changes in the physiology of many different tissues resulting in a
spectrum of pathology. Nonetheless, many lines of evidence suggest that ageing is driven …

Stem cells derived from human dental pulp tissue (DP‐MSC) differ from the other
mesenchymal stem cells prepared from bone marrow or adipose tissue due to their …

Mesenchymal (stromal) stem cells (MSCs) constitute populations of mesodermal multipotent
cells involved in tissue regeneration and homeostasis in many different organs. Here we …

Phenotypic variation in skeletal traits and diseases is the product of genetic and
environmental factors. Epigenetic mechanisms include information‐containing factors, other …

Insufficient activity of the bone-forming osteoblasts leads to low bone mass and predisposes
to fragility fractures. The functional capacity of human mesenchymal stem cells (hMSCs), the …

Melatonin is a bioamine produced primarily in the pineal gland, although peripheral sites,
including the gut, may also be its minor source. Melatonin regulates various functions …

Bone aging is characterized by an imbalance in the physiological and pathological
processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis …

Therapeutic targeting of PI3K-Akt-mTOR is considered a possible strategy in human acute
myeloid leukaemia (AML); the most important rationale being the proapoptotic and …

The COVID-19 pandemic has affected African American populations disproportionately with
respect to prevalence, and mortality. Expression profiles represent snapshots of combined …

There is mounting evidence in the literature that mesenchymal stromal/stem cell (MSC) like
populations derived from different tissues, undergo epigenetic changes during aging …