Structural insights into type III secretion systems of the bacterial flagellum and injectisome
LJ Worrall, DD Majewski… - Annual Review of …, 2023 - annualreviews.org
Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
[HTML][HTML] Recent structural advances towards understanding of the bacterial type III secretion injectisome
J Jenkins, LJ Worrall, NCJ Strynadka - Trends in Biochemical Sciences, 2022 - cell.com
The bacterial injectisome is a structurally conserved, syringe-shaped nanomachine that
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
FlaG competes with FliS–flagellin complexes for access to FlhA in the flagellar T3SS to control Campylobacter jejuni filament length
AA Waller, DA Ribardo, DR Hendrixson - Proceedings of the National …, 2024 - pnas.org
Bacteria power rotation of an extracellular flagellar filament for swimming motility.
Thousands of flagellin subunits compose the flagellar filament, which extends several …
Thousands of flagellin subunits compose the flagellar filament, which extends several …
Direct interaction of a chaperone-bound type III secretion substrate with the export gate
D Gilzer, M Schreiner, HH Niemann - Nature Communications, 2022 - nature.com
Several gram-negative bacteria employ type III secretion systems (T3SS) to inject effector
proteins into eukaryotic host cells directly from the bacterial cytoplasm. The export gate SctV …
proteins into eukaryotic host cells directly from the bacterial cytoplasm. The export gate SctV …
Conserved GYXLI motif of FlhA is involved in dynamic domain motions of FlhA required for flagellar protein export
Flagellar structural subunits are transported via the flagellar type III secretion system (fT3SS)
and assemble at the distal end of the growing flagellar structure. The C-terminal cytoplasmic …
and assemble at the distal end of the growing flagellar structure. The C-terminal cytoplasmic …
Manipulation of host immune defenses by effector proteins delivered from multiple secretion systems of Salmonella and its application in vaccine research
G Zhou, Y Zhao, Q Ma, Q Li, S Wang, H Shi - Frontiers in Immunology, 2023 - frontiersin.org
Salmonella is an important zoonotic bacterial species and hazardous for the health of
human beings and livestock globally. Depending on the host, Salmonella can cause …
human beings and livestock globally. Depending on the host, Salmonella can cause …
Primary architecture and energy requirements of Type III and Type IV secretion systems
E Cabezón, F Valenzuela-Gómez… - Frontiers in Cellular and …, 2023 - frontiersin.org
Many pathogens use Type III and Type IV protein secretion systems to secrete virulence
factors from the bacterial cytosol into host cells. These systems operate through a one-step …
factors from the bacterial cytosol into host cells. These systems operate through a one-step …
Structural dynamics of the functional nonameric type III translocase export gate
Type III protein secretion is widespread in Gram-negative pathogens. It comprises the
injectisome with a surface-exposed needle and an inner membrane translocase. The …
injectisome with a surface-exposed needle and an inner membrane translocase. The …
Structural and functional analysis of SsaV cytoplasmic domain and variable linker states in the context of the InvA-SsaV chimeric protein
J Xu, J Wang, A Liu, Y Zhang, X Gao - Microbiology Spectrum, 2021 - Am Soc Microbiol
The type III secretion (T3S) injectisome is a syringe-like protein-delivery nanomachine
widely utilized by Gram-negative bacteria. It can deliver effector proteins directly from …
widely utilized by Gram-negative bacteria. It can deliver effector proteins directly from …
鸡白痢沙门菌ssaV 基因缺失株的构建及其生物学特性分析.
徐冠冰， 王利平， 崔素宁， 张震… - Journal of Henan …, 2021 - search.ebscohost.com
为探究ssaV 基因对鸡白痢沙门菌致病性的影响, 利用同源重组技术, 以pKD3 质粒为模板,
设计同源臂, 扩增外源线性DNA 片段, 将该片段电转化入含有pKD46 的鸡白痢沙门菌C79-13 …
设计同源臂, 扩增外源线性DNA 片段, 将该片段电转化入含有pKD46 的鸡白痢沙门菌C79-13 …