Exploring the potential of cell-derived vesicles for transient delivery of gene editing payloads

K Leandro, D Rufino-Ramos, K Breyne… - Advanced Drug Delivery …, 2024 - Elsevier
Gene editing technologies have the potential to correct genetic disorders by modifying,
inserting, or deleting specific DNA sequences or genes, paving the way for a new class of …

Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles

AM Zickler, X Liang, D Gupta, D Mamand, MD Luca… - bioRxiv, 2023 - biorxiv.org
Messenger RNA (mRNA) has emerged as an attractive therapeutic molecule for a range of
clinical applications. For in vivo functionality, mRNA therapeutics require encapsulation into …