The success of oil-based plastics and the continued growth of production and utilisation can
be attributed to their cost, durability, strength to weight ratio, and eight contributions to the …

Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

The aortic valve exhibits complex three-dimensional (3D) anatomy and heterogeneity
essential for the long-term efficient biomechanical function. These are, however, challenging …

The creation of a living heart valve is a much-wanted alternative for current valve prostheses
that suffer from limited durability and thromboembolic complications. Current strategies to …

Surgical management of tetralogy of Fallot (TOF) results in anatomic and functional
abnormalities in the majority of patients. Although right ventricular volume load due to …

Valvular heart disease is a major cause of morbidity and mortality worldwide. Current heart
valve prostheses have considerable clinical limitations due to their artificial, nonliving nature …

Cardiovascular tissue engineering aims to find solutions for the suboptimal regeneration of
heart valves, arteries and myocardium by creating 'living'tissue replacements outside (in …

The current clinical solutions, including mechanical and bioprosthetic valves for valvular
heart diseases, are plagued by coagulation, calcification, nondurability, and the inability to …

The aortic valve regulates unidirectional flow of oxygenated blood to the myocardium and
arterial system. The natural anatomical geometry and microstructural complexity ensures …

Abstract Treatment of congenital heart defects in children requiring right ventricular outflow
tract reconstruction typically involves multiple open-heart surgeries because all existing graft …