Fluorescent proteins and genetically encoded biosensors

M Wang, Y Da, Y Tian - Chemical Society Reviews, 2023 - pubs.rsc.org
The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

Comprehensive review on bimolecular fluorescence complementation and its application in deciphering protein–protein interactions in cell signaling pathways

H Ren, Q Ou, Q Pu, Y Lou, X Yang, Y Han… - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Signaling pathways are responsible for transmitting information between cells and
regulating cell growth, differentiation, and death. Proteins in cells form complexes by …

Molecular Spies in Action: Genetically Encoded Fluorescent Biosensors Light up Cellular Signals

AMM Gest, AZ Sahan, Y Zhong, W Lin, S Mehta… - Chemical …, 2024 - ACS Publications
Cellular function is controlled through intricate networks of signals, which lead to the myriad
pathways governing cell fate. Fluorescent biosensors have enabled the study of these …

Chemical and Biological Strategies for Profiling Protein‐Protein Interactions in Living Cells

YY Wang, W Li, BC Ye, XB Bi - Chemistry–An Asian Journal, 2023 - Wiley Online Library
Protein‐protein interactions (PPIs) play critical roles in almost all cellular signal transduction
events. Characterization of PPIs without interfering with the functions of intact cells is very …

A Background Assessable and Correctable Bimolecular Fluorescence Complementation System for Nanoscopic Single-Molecule Imaging of Intracellular Protein …

S Mao, Y Ying, Z Ma, Y Yang, AK Chen - ACS nano, 2021 - ACS Publications
Bimolecular Fluorescence Complementation (BiFC) is a versatile approach for intracellular
analysis of protein–protein interactions (PPIs), but the tendency of the split fluorescent …

Identification of relevant protein interactions with partial knowledge: A complex network and deep learning approach

P Ortiz-Vilchis, JS De-la-Cruz-García… - Biology, 2023 - mdpi.com
Simple Summary Protein–protein interactions (PPIs) are the basis for understanding cellular
events in biological systems. Experimental biochemical, molecular, and genetic methods …

Advances in Bio‐Optical Imaging Systems for Spatiotemporal Monitoring of Intestinal Bacteria

T Pan, L Su, Y Zhang, L Xu… - Molecular Nutrition & Food …, 2024 - Wiley Online Library
Vast and complex intestinal communities are regulated and balanced through interactions
with their host organisms, and disruption of gut microbial balance can cause a variety of …

[HTML][HTML] Methodological approaches for the analysis of transmembrane domain interactions: A systematic review

G Duart, B Grau, I Mingarro, L Martinez-Gil - Biochimica et Biophysica Acta …, 2021 - Elsevier
The study of protein-protein interactions (PPI) has proven fundamental for the understanding
of the most relevant cell processes. Any protein domain can participate in PPI, including …

The smallest near-infrared fluorescence complementation system for imaging protein–protein and RNA–protein interactions

M Chen, C Yan, L Zheng, XE Zhang - Chemical Science, 2022 - pubs.rsc.org
Bimolecular fluorescence complementation (BiFC) and its derivative molecular biosensor
systems provide effective tools for visualizing biomolecular interactions. The introduction of …

Novel Bimolecular Fluorescence Complementation (BiFC) Assay for Visualization of the Protein–Protein Interactions and Cellular Protein Complex Localizations

Z Shi, X Gao, W Zhang, B Chen, M Wang, K Liao… - Molecular …, 2024 - Springer
Investigations of protein–protein interactions (PPIs) are of paramount importance for
comprehending cellular processes within biological systems. The bimolecular fluorescence …