Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of
death due to cancer worldwide. The gastric mucosa often undergoes many years of …

Trefoil factor (TFF) peptides, with a 40-amino acid motif and including six conserved cysteine
residues that form intramolecular disulfide bonds, are a family of mucin-associated secretory …

Macropinocytosis is differentiated from other types of endocytosis by its unique susceptibility
to inhibitors of Na+/H+ exchange. Yet, the functional relationship between Na+/H+ exchange …

Latex from Caricaceae contains proteolytic enzymes localized in the fruit, which are used
ethnopharmacologically to treat digestive disorders. Some of these proteins display …

Cysteine proteinases are involved in virtually every aspect of plant physiology and
development. They play a role in development, senescence, programmed cell death …

Abstract The Slc9 family of Na+/H+ exchangers (NHEs) plays a critical role in electroneutral
exchange of Na+ and H+ in the mammalian intestine as well as other absorptive and …

Several members of the SLC9A family of Na+/H+ exchangers are expressed in the gut, with
varying expression patterns and cellular localization. Not only do they participate in the …

Excessive alcohol consumption can induce gastric mucosal damage. The present work
aimed to examine the protective effect of wheat peptides against ethanol-induced gastric …

Ethnopharmacological relevance Gastric ulcer (GU) is the injury of the gastric mucosa
caused by the stimulation of various pathogenic factors penetrating the deep mucosal …

Trefoil factor (TFF) peptides are pivotal for gastric restitution after surface epithelial damage,
but TFF cellular targets that promote cell migration are poorly understood. Conversely, Na/H …