Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

The ubiquitin system is complex, multifaceted, and is crucial for the modulation of a vast
number of cellular processes. Ubiquitination is tightly regulated at different levels by a range …

Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

Medicinal plants are being used for therapeutic purposes since the dawn of human
civilization. The therapeutic efficacy of medicinal plants is due to the presence of wide range …

Multiple myeloma, which ranks as the second most common hematological malignancy, is
known for its great genetic heterogeneity. One pathway, however, stands out in this diverse …

Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …

Curcumin, the active ingredient in Curcuma longa, has been in medicinal use since ancient
times. However, the therapeutic targets and signaling cascades modulated by curcumin …

Alternative treatments for neoplastic diseases with new drugs are necessary because the
clinical effectiveness of chemotherapy is often reduced by collateral effects. Several natural …

Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

Cancer arises through a complex interplay between genetic, behavioral, metabolic, and
environmental factors that combined trigger cellular changes that over time promote …