Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Endometriosis is a prevalent gynecological condition associated with pelvic pain and
infertility. Despite more than a century of research, the etiology of endometriosis still eludes …

DNA methylation is an epigenetic mark that is essential for many biological processes and is
linked to diseases such as cancer. Methylation is usually associated with transcriptional …

Chemical stressors can induce epigenomic changes, ie, changes that are transferred to the
next generation, even when the stressor is removed. Literature on chemical induced …

Breast cancer-associated fibroblasts (CAFs) have a crucial role in tumor initiation,
metastasis and therapeutic resistance by secreting various growth factors, cytokines …

Simple Summary Loss of DNA methylation is often observed in human tumors, but how this
epigenetic alteration impacts the transcriptome of cancer cells remains largely undefined. So …

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease, in which
pathogenesis is not clear. Many research demonstrated that fibroblast-like synoviocytes …

Methyl-CpG-binding domain protein 2 (Mbd2), a reader of DNA methylation, has been
implicated in different types of malignancies, including breast cancer. However, the exact …

In a number of human cancers, NTN 1 upregulation inhibits apoptosis induced by its so‐
called dependence receptors DCC and UNC 5H, thus promoting tumor progression. In other …

Diabetes causes cardiomyopathy and increases the risk of heart failure independent of
hypertension and cardiac fibrosis disease. However, the molecular mechanism of …