Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

New Findings What is the topic of this review? The manuscript collectively combines the
experimental observations from> 100 publications focusing on the regulation of cerebral …

This article presents a historical overview and an up-to-date review of hyperthermia-induced
fatigue during exercise in the heat. Exercise in the heat is associated with a …

Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

Abstract Background and Purpose Cognitive decline is an important contributor to disability
in patients with chronic heart failure, affecting 25%–50% of patients. The aim of this review is …

Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

Exercise is a uniquely effective and pluripotent medicine against several noncommunicable
diseases of westernised lifestyles, including protection against neurodegenerative …

Introduction Cerebral autoregulation (CA) is a theoretical construct characterized by the
relationship between mean arterial pressure (MAP) and cerebral blood flow (CBF). We …

Importance Little is known about the associations of strict blood pressure (BP) control with
microstructural changes in small vessel disease markers. Objective To investigate the …

Increases in arterial carbon dioxide tension (hypercapnia) elicit potent vasodilation of
cerebral arterioles. Recent studies have also reported vasodilation of the internal carotid …