Objectives Reproductive malfunctions after chemotherapy still are a reason of reducing
fertility and need specialized intensive care. The aim of this review was to investigate the …

Infertility is a major global health issue and male factors account for half of all infertility
cases. One of the causes of male infertility is the loss of spermatogonial stem cells, which …

In the present study, effect of doxorubicin at 2 mg/kg b. wt.(i/p), alone, once in a wk for 4 wks
and in combination with vitamin E at 250 and 500 mg/kg b. wt., orally, daily for 4 wks was …

The protective effect of taurine against doxorubicin-induced testicular oxidative stress and
apoptosis was investigated in rats. Male rats 8 weeks of age were treated with doxorubicin …

Background: Doxorubicin (DOX), an anthracycline antibiotic, is a widely used anticancer
agent. In spite of its high antitumor efficacy, the use of DOX in clinical chemotherapy is …

Background Cisplatin (CP), an effective anticancer agent, carries the risk of impairing
testicular function leading to infertility. The present study aimed at evaluating the protective …

The present study aims to investigate the protective effects of zinc oxide nanoparticles (ZnO
NPs) on doxorubicin-induced testicular injury. Forty mature male rats were randomly …

Objective: Doxorubicin (DOX) is a broad spectrum chemotherapeutic agent used in the
treatment of several malignancies. The use of DOX in clinical chemotherapy has been …

This study was conducted to evaluate the protective role of Pleurotus eryngii extract (PE)
and Pleurotus eryngii extract‐loaded chitosan nanoparticles (PE‐CSNP) against …

Background Male testicular dysfunction is a considerable complication of anti-cancer
therapies, including chemotherapy and radiotherapy, partly due to the increased oxidative …