Active site structure and catalytic mechanisms of human peroxidases

PG Furtmüller, M Zederbauer, W Jantschko… - Archives of biochemistry …, 2006 - Elsevier
Myeloperoxidase (MPO), eosinophil peroxidase, lactoperoxidase, and thyroid peroxidase
are heme-containing oxidoreductases (EC 1.7. 1.11), which bind ligands and/or undergo a …

Autocatalytic radical reactions in physiological prosthetic heme modification

C Colas, PR Ortiz de Montellano - Chemical reviews, 2003 - ACS Publications
The complex of iron with a porphyrin, usually protoporphyrin IX, is a highly versatile
prosthetic group that has been utilized by nature in the assembly of a large variety of …

[图书][B] Handbook Of Porphyrin Science: With Applications To Chemistry, Physics, Materials Science, Engineering, Biology And Medicine (Volumes 6-10)

KM Kadish, R Guilard, KM Smith - 2010 - books.google.com
This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

[HTML][HTML] Werner and Ingbar's the thyroid: a fundamental and clinical text

P Kopp, DS Cooper, LE Braverman - 2005 - doctorlib.info
Thyroid hormone biosynthesis, storage, and secretion require a series of highly regulated
steps. Iodide, the rate-limiting substrate for thyroid hormone synthesis, is actively transported …

4B Thyroid hormone synthesis

P Kopp - Werner & Ingbar's The Thyroid: A Fundamental and …, 2005 - books.google.com
Thyroid hormone biosynthesis, storage, and secretion require a series of highly regulated
steps. Iodide, the ratelimiting substrate for thyroid hormone synthesis, is actively transported …

Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function

CS Nunemaker, HG Chung, GM Verrilli… - Journal of …, 2014 - joe.bioscientifica.com
The soy phytoestrogen, genistein, induces thymic atrophy when administered to
ovariectomized mice by injection or in the diet. Injected genistein also causes decreased …

Bioactive proteins in bovine colostrum and effects of heating, drying and irradiation

DEW Chatterton, S Aagaard, TH Hansen… - Food & function, 2020 - pubs.rsc.org
Bovine colostrum (BC) contains bioactive proteins, such as immunoglobulin G (IgG),
lactoferrin (LF) and lactoperoxidase (LP). BC was subjected to low-temperature, long-time …

Contributions of myeloperoxidase to proinflammatory events: more than an antimicrobial system

WM Nauseef - International journal of hematology, 2001 - Springer
Optimal oxygen-dependent antimicrobial activity of circulating polymorphonuclear
leukocytes reflects the synergistic effects of the myeloperoxidase (MPO)—hydrogen …

Asp-225 and Glu-375 in autocatalytic attachment of the prosthetic heme group of lactoperoxidase

C Colas, JM Kuo, PRO de Montellano - Journal of Biological Chemistry, 2002 - ASBMB
The heme in lactoperoxidase is attached to the protein by ester bonds between the heme 1-
and 5-methyl groups and Glu-375 and Asp-275, respectively. To investigate the cross …

Spin trapping and protein cross-linking of the lactoperoxidase protein radical

OM Lardinois, KF Medzihradszky… - Journal of Biological …, 1999 - ASBMB
Lactoperoxidase (LPO) reacts with H 2 O 2 to sequentially give two Compound I
intermediates: the first with a ferryl (Fe IV= O) species and a porphyrin radical cation, and the …