Targeting carbonic anhydrases for the management of hypoxic metastatic tumors
CT Supuran - Expert Opinion on Therapeutic Patents, 2023 - Taylor & Francis
Introduction Several isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
are connected with tumorigenesis. Hypoxic tumors overexpress CA IX and XII as a …
are connected with tumorigenesis. Hypoxic tumors overexpress CA IX and XII as a …
Nano-based drug delivery system for therapeutics: A comprehensive review
S Prakash - Biomedical Physics & Engineering Express, 2023 - iopscience.iop.org
Nanomedicine and nano-delivery systems hold unlimited potential in the developing
sciences, where nanoscale carriers are employed to efficiently deliver therapeutic drugs at …
sciences, where nanoscale carriers are employed to efficiently deliver therapeutic drugs at …
Metal–Organic Framework Nanocomposites in Conquering Hypoxia for Tumor Therapy
S Zhou, F Jia, Y Wei, J Du, J Liu… - Advanced Functional …, 2024 - Wiley Online Library
Hypoxia, as a distinctive feature of tumors, is closely related to tumor recurrence, metastasis,
and treatment resistance. Metal–organic framework (MOF) exhibits an increasing number of …
and treatment resistance. Metal–organic framework (MOF) exhibits an increasing number of …
Synthesis and Enzymatic Evaluation of a Small Library of Substituted Phenylsulfonamido-Alkyl Sulfamates towards Carbonic Anhydrase II
TC Denner, NV Heise, A Al-Harrasi, R Csuk - Molecules, 2024 - mdpi.com
A small library of 79 substituted phenylsulfonamidoalkyl sulfamates, 1b–79b, was
synthesized starting from arylsulfonyl chlorides and amino alcohols with different numbers of …
synthesized starting from arylsulfonyl chlorides and amino alcohols with different numbers of …
Immunophenotypes and Tumor Immune Microenvironment in Hepatocellular Carcinoma With Macrotrabecular Massive and Vessels Encapsulating Tumor Clusters
J Akiba, M Nakayama, R Kondo, H Kusano… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Recently, vessels encapsulating tumor clusters (VETC) pattern and
macrotrabecular massive (MTM) pattern of hepatocellular carcinoma (HCC) have been …
macrotrabecular massive (MTM) pattern of hepatocellular carcinoma (HCC) have been …