[HTML][HTML] Regulatory roles for SOX11 in development, stem cells and cancer
SM Tsang, E Oliemuller, BA Howard - Seminars in cancer biology, 2020 - Elsevier
The transcription factor SOX11 (SRY-related high-mobility-group (HMG) box 11), a member
of the SOXC group, is expressed during embryogenesis but largely absent in most adult …
of the SOXC group, is expressed during embryogenesis but largely absent in most adult …
SOX11: friend or foe in tumor prevention and carcinogenesis?
Z Yang, S Jiang, C Lu, T Ji, W Yang… - … in medical oncology, 2019 - journals.sagepub.com
Sex-determining region Y-related high-mobility-group box transcription factor 11 (SOX11) is
an essential member of the SOX transcription factors and has been highlighted as an …
an essential member of the SOX transcription factors and has been highlighted as an …
SOX11 promotes epithelial/mesenchymal hybrid state and alters tropism of invasive breast cancer cells
E Oliemuller, R Newman, SM Tsang, S Foo… - Elife, 2020 - elifesciences.org
SOX11 is an embryonic mammary epithelial marker that is normally silenced prior to birth.
High SOX11 levels in breast tumours are significantly associated with distant metastasis and …
High SOX11 levels in breast tumours are significantly associated with distant metastasis and …
Phosphorylation-dependent subfunctionalization of the calcium-dependent protein kinase CPK28
Calcium (Ca2+)-dependent protein kinases (CDPKs or CPKs) are a unique family of Ca2+
sensor/kinase-effector proteins with diverse functions in plants. In Arabidopsis thaliana …
sensor/kinase-effector proteins with diverse functions in plants. In Arabidopsis thaliana …
[HTML][HTML] Post-translational modification of SOX family proteins: Key biochemical targets in cancer?
Sox proteins are a family of lineage-associated transcription factors. They regulate
expression of genes involved in control of self-renewal and multipotency in both …
expression of genes involved in control of self-renewal and multipotency in both …
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex
F Da Silva, K Zhang, A Pinson, E Fatti… - The EMBO …, 2021 - embopress.org
The role of WNT/β‐catenin signalling in mouse neocortex development remains ambiguous.
Most studies demonstrate that WNT/β‐catenin regulates progenitor self‐renewal but others …
Most studies demonstrate that WNT/β‐catenin regulates progenitor self‐renewal but others …
Inferring differential subcellular localisation in comparative spatial proteomics using BANDLE
The steady-state localisation of proteins provides vital insight into their function. These
localisations are context specific with proteins translocating between different subcellular …
localisations are context specific with proteins translocating between different subcellular …
Exploring the reciprocity between pioneer factors and development
MM Freund, MM Harrison, EF Torres-Zelada - Development, 2024 - journals.biologists.com
Development is regulated by coordinated changes in gene expression. Control of these
changes in expression is largely governed by the binding of transcription factors to specific …
changes in expression is largely governed by the binding of transcription factors to specific …
Spatially aware self-representation learning for tissue structure characterization and spatial functional genes identification
Spatially resolved transcriptomics (SRT) enable the comprehensive characterization of
transcriptomic profiles in the context of tissue microenvironments. Unveiling spatial …
transcriptomic profiles in the context of tissue microenvironments. Unveiling spatial …
Moving profiling spatial proteomics beyond discrete classification
The spatial subcellular proteome is a dynamic environment; one that can be perturbed by
molecular cues and regulated by post‐translational modifications. Compartmentalization of …
molecular cues and regulated by post‐translational modifications. Compartmentalization of …