Tertiary lymphoid structures: autoimmunity goes local

E Pipi, S Nayar, DH Gardner, S Colafrancesco… - Frontiers in …, 2018 - frontiersin.org
Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune
diseases. TLS present features of secondary lymphoid organs such as segregated T and B …

Monitoring of immunoglobulin N- and O-glycosylation in health and disease

N de Haan, D Falck, M Wuhrer - Glycobiology, 2020 - academic.oup.com
Protein N-and O-glycosylation are well known co-and post-translational modifications of
immunoglobulins. Antibody glycosylation on the Fab and Fc portion is known to influence …

Structural characterization of N‐linked glycans in the receptor binding domain of the SARS‐CoV‐2 spike protein and their interactions with human lectins

MP Lenza, I Oyenarte, T Diercks… - Angewandte …, 2020 - Wiley Online Library
The glycan structures of the receptor binding domain of the SARS‐CoV2 spike glycoprotein
expressed in human HEK293F cells have been studied by using NMR. The different …

Imaging mass spectrometry and lectin analysis of N-linked glycans in carbohydrate antigen–defined pancreatic cancer tissues

CT McDowell, Z Klamer, J Hall, CA West… - Molecular & Cellular …, 2021 - ASBMB
The early detection of pancreatic ductal adenocarcinoma (PDAC) is a complex clinical
obstacle yet is key to improving the overall likelihood of patient survival. Current and …

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples

GSM Lageveen-Kammeijer, N de Haan… - Nature …, 2019 - nature.com
The in-depth, high-sensitivity characterization of the glycome from complex biological
samples, such as biofluids and tissues, is of utmost importance in basic biological research …

Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on the early and late stages

F Coutant, P Miossec - Current opinion in rheumatology, 2020 - journals.lww.com
Evolving concepts of the pathogenesis of rheumatoid arthriti... : Current Opinion in
Rheumatology Evolving concepts of the pathogenesis of rheumatoid arthritis with focus on …

Advances in mass spectrometry‐based glycomics

X Dong, Y Huang, BG Cho, J Zhong, S Gautam… - …, 2018 - Wiley Online Library
The diversification of the chemical properties and biological functions of proteins is attained
through posttranslational modifications, such as glycosylation. Glycans, which are covalently …

A label-free and anti-interference dual-channel SPR fiber optic sensor with self-compensation for biomarker detection

Q Wang, H Song, A Zhu, F Qiu - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
In this work, we report a self-compensating, label-free, and anti-interference surface
plasmon resonance (SPR) fiber biosensor based on a cascaded U-shaped multimode fiber …

Enrichment driven glycoproteomics: New materials, new methods, and beyond

Y Xiong, M Li, Y Liu, X Liang, G Qing - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Glycoproteomics is a rapidly growing field that aims to identify and characterize protein
glycosylation events at a system level. However, the analysis of protein glycosylation in …

Antibody Fc glycosylation discriminates between latent and active tuberculosis

LL Lu, J Das, PS Grace, SM Fortune… - The Journal of …, 2020 - academic.oup.com
Background Mycobacterium tuberculosis remains a global health problem and clinical
management is complicated by difficulty in discriminating between latent infection and active …