Impact of childhood malnutrition on host defense and infection
MK Ibrahim, M Zambruni, CL Melby… - Clinical microbiology …, 2017 - Am Soc Microbiol
The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …
malnutrition and infection contributes substantially to childhood morbidity and mortality …
Vitamin D, disease and therapeutic opportunities
LA Plum, HF DeLuca - Nature reviews Drug discovery, 2010 - nature.com
The discovery of the vitamin D endocrine system and a receptor for the hormonal form, 1α,
25-dihydroxyvitamin D3, has brought a new understanding of the relationship between …
25-dihydroxyvitamin D3, has brought a new understanding of the relationship between …
Vitamin D is required for IFN-γ–mediated antimicrobial activity of human macrophages
M Fabri, S Stenger, DM Shin, JM Yuk, PT Liu… - Science translational …, 2011 - science.org
Control of tuberculosis worldwide depends on our understanding of human immune
mechanisms, which combat the infection. Acquired T cell responses are critical for host …
mechanisms, which combat the infection. Acquired T cell responses are critical for host …
[HTML][HTML] Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection
Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …
Diabetes and immunity to tuberculosis
N Martinez, H Kornfeld - European journal of immunology, 2014 - Wiley Online Library
The dual burden of tuberculosis (TB) and diabetes has attracted much attention in the past
decade as diabetes prevalence has increased dramatically in countries already afflicted with …
decade as diabetes prevalence has increased dramatically in countries already afflicted with …
Vitamin D accelerates clinical recovery from tuberculosis: results of the SUCCINCT Study [Supplementary Cholecalciferol in recovery from tuberculosis]. A randomized …
Background Vitamin D enhances host protective immune responses to Mycobacterium
tuberculosis by suppressing Interferon-gamma (IFN-g) and reducing disease associated …
tuberculosis by suppressing Interferon-gamma (IFN-g) and reducing disease associated …
Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis
Background Few studies have evaluated the association between preexisting vitamin D
deficiency and incident tuberculosis (TB). We assessed the impact of baseline vitamins D …
deficiency and incident tuberculosis (TB). We assessed the impact of baseline vitamins D …
Vitamin D and innate and adaptive immunity
M Hewison - Vitamins & hormones, 2011 - Elsevier
In the last 5 years there has been renewed interest in the health benefits of vitamin D. A
central feature of this revival has been new information concerning the nonclassical effects …
central feature of this revival has been new information concerning the nonclassical effects …
Antimicrobial implications of vitamin D
DA Youssef, CWT Miller, AM El-Abbassi… - Dermato …, 2011 - Taylor & Francis
Evidence exists that vitamin D has a potential antimicrobial activity and its deficiency has
deleterious effects on general well-being and longevity. Vitamin D may reduce the risk of …
deleterious effects on general well-being and longevity. Vitamin D may reduce the risk of …