Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings

L Ricciardi, M Apps, S Little - npj Parkinson's Disease, 2023 - nature.com
Neuropsychiatric mood and motivation symptoms (depression, anxiety, apathy, impulse
control disorders) in Parkinson's disease (PD) are highly disabling, difficult to treat and …

Closed-loop adaptive deep brain stimulation in Parkinson's disease: procedures to achieve it and future perspectives

S Wang, G Zhu, L Shi, C Zhang, B Wu… - Journal of …, 2023 - content.iospress.com
Parkinson's disease (PD) is a neurodegenerative disease with a heavy burden on patients,
families, and society. Deep brain stimulation (DBS) can improve the symptoms of PD …

Clinical neuroscience and neurotechnology: An amazing symbiosis

A Cometa, A Falasconi, M Biasizzo, J Carpaneto… - Iscience, 2022 - cell.com
In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices
able to record and stimulate electrical activity in the nervous system. These technologies …

Impulsivity is associated with firing regularity in parkinsonian ventral subthalamic nucleus

M Vissani, F Micheli, G Pecchioli… - Annals of Clinical …, 2022 - Wiley Online Library
Impulsive–compulsive behaviors (ICB) are over‐represented in Parkinson's disease (PD)
patients. Neurons in the ventral subthalamic nucleus (STN) might play a predominant role in …

Low-Frequency Activity in Dorsal Subthalamic Nucleus Predicts Impulsivity Improvement Following Deep Brain Stimulation in Parkinsonian Patients

A Kaymak, L Cubeddu, M Vissani, F Taddeini… - medRxiv, 2024 - medrxiv.org
Objective. The progression of impulsive-compulsive behaviors (ICB) in Parkinson's Disease
(PD) following subthalamic deep brain stimulation (DBS) surgery displays a large inter …

Mapping the electrophysiological structure of dystonic Globus Pallidus pars interna through intraoperative microelectrode recordings

A Kaymak, M Vissani, S Rinaldo, R Eleopra, L Romito… - medRxiv, 2022 - medrxiv.org
Abstract Objective The Globus Pallidus pars interna (GPi) is one of the main targets for Deep
Brain Stimulation (DBS) therapies for dystonia and other movement disorders. Still, a …

A retrospective study on deep brain stimulation effects on impulsivity in Parkinsonian patients

L Cubeddu - 2023 - webthesis.biblio.polito.it
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms
such as tremors, rigidity and bradykinesia and non-motor symptoms such as mood …