Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

Ischemic cardiomyopathy and heart failure after acute myocardial infarction

MG Del Buono, F Moroni, RA Montone… - Current Cardiology …, 2022 - Springer
Abstract Purpose of Review Ischemic cardiomyopathy refers to systolic left ventricular
dysfunction in the setting of obstructive coronary artery disease and represents the most …

Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Optimization of mesenchymal stromal cell (MSC) manufacturing processes for a better therapeutic outcome

ME Fernández-Santos, M Garcia-Arranz… - Frontiers in …, 2022 - frontiersin.org
MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

Interleukin-1 blockade with anakinra and heart failure following ST-segment elevation myocardial infarction: results from a pooled analysis of the VCUART clinical …

A Abbate, GF Wohlford, MG Del Buono… - European Heart …, 2022 - academic.oup.com
Aims ST-segment elevation myocardial infarction (STEMI) is associated with an intense
acute inflammatory response and an increased risk of death and heart failure (HF). In this …

[HTML][HTML] Treatment strategies of acute myocardial infarction: updates on revascularization, pharmacological therapy, and beyond

Y Saito, K Oyama, K Tsujita, S Yasuda, Y Kobayashi - Journal of cardiology, 2023 - Elsevier
Owing to recent advances in early reperfusion strategies, pharmacological therapy,
standardized care, and the identification of vulnerable patient subsets, the prognosis of …

Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI

X Ai, B Yan, N Witman, Y Gong, L Yang, Y Tan… - Molecular Therapy, 2023 - cell.com
Cell-based therapies offer an exciting and novel treatment for heart repair following
myocardial infarction (MI). However, these therapies often suffer from poor cell viability and …

Therapies to prevent post-infarction remodelling: From repair to regeneration

P Contessotto, A Pandit - Biomaterials, 2021 - Elsevier
Myocardial infarction is the first cause of worldwide mortality, with an increasing incidence
also reported in developing countries. Over the past decades, preclinical research and …

Heart failure after ST-elevation myocardial infarction: beyond left ventricular adverse remodeling

MG Del Buono, CM Garmendia, IM Seropian… - Current problems in …, 2023 - Elsevier
ST-segment elevation myocardial infarction (STEMI) remains a significant source of
morbidity and mortality worldwide. Despite advances in treatment leading to a significant …

Myocardial regeneration protocols towards the routine clinical scenario: An unseemly path from bench to bedside

N Salerno, L Salerno, F Marino, M Scalise… - …, 2022 - thelancet.com
Heart failure secondary to cardiomyocyte loss and/or dysfunction is the number one killer
worldwide. The field of myocardial regeneration with its far-reaching primary goal of cardiac …