Organocatalysis in aqueous media

MP van Der Helm, B Klemm, R Eelkema - Nature Reviews Chemistry, 2019 - nature.com
Even though enzymes are the cornerstones of living systems, it has so far proven difficult to
deploy artificial catalysts in a biological setting. Organocatalysts are arguably well-suited …

Ce (III) and Lu (III) metal–organic frameworks with Lewis acid metal sites: Preparation, sorption properties and catalytic activity in Knoevenagel condensation

M Almáši, V Zeleňák, M Opanasenko, I Císařová - Catalysis today, 2015 - Elsevier
Two novel coordination polymers with composition {[Ln (BTC)(H 2 O)]· DMF} n (where Ln=
Ce (III)(1) and Lu (III)(2), BTC= benzene-1, 3, 5-tricarboxylate, DMF= N, N …

Urea-catalyzed multicomponent synthesis of 4-arylideneisoxazol-5(4H)-one derivatives under green conditions

F Haydari, H Kiyani - Research on Chemical Intermediates, 2023 - Springer
A simple and green one-pot, three-component procedure was used for the efficient synthesis
of different isoxazol-5 (4 H)-ones from aryl/heteroaryl aldehydes, hydroxylamine …

Direct catalytic asymmetric synthesis of β-hydroxy acids from malonic acid

H Gao, Z Luo, P Ge, J He, F Zhou, P Zheng… - Organic letters, 2015 - ACS Publications
A nickel (II) catalyzed asymmetric synthesis of β-hydroxy acids from malonic acid and
ketones was developed, revealing for the first time the synthetic utility of malonic acid in the …

Sustainable Synthesis of p-Hydroxycinnamic Diacids through Proline-Mediated Knoevenagel Condensation in Ethanol: An Access to Potent Phenolic UV Filters and …

B Rioux, C Peyrot, MM Mention, F Brunissen, F Allais - Antioxidants, 2020 - mdpi.com
p-Hydroxycinnamic diacids are reaction intermediates of the classical Knoevenagel–
Doebner condensation between malonic acid and benzaldehydes. As they are generally …

Ionic liquid [Dabco-H][AcO] as a highly efficient and recyclable catalyst for the synthesis of various bisenol derivatives via domino Knoevenagel–Michael reaction in …

C Yang, WQ Su, DZ Xu - RSC advances, 2016 - pubs.rsc.org
A simple and highly efficient domino Knoevenagel–Michael reaction procedure for the
synthesis of a series of bisenols has been successfully developed. In the presence of 1, 4 …

Base-promoted cascade approach for the preparation of reduced knoevenagel adducts using hantzsch esters as reducing agent in water

T He, R Shi, Y Gong, G Jiang, M Liu, S Qian, Z Wang - Synlett, 2016 - thieme-connect.com
A cascade Knoevenagel condensation–reduction approach, which was carried out in water,
has been reported. Using Hantzsch esters as reducing agent, under the promotion of base …

Solvent-free synthesis of novel vanillidene derivatives of Meldrum's acid: biological evaluation, DNA and BSA binding study

N Janković, J Muškinja, Z Ratković, Z Bugarčić… - RSC …, 2016 - pubs.rsc.org
A series of novel O-alkyl vanillidene derivatives containing Meldrum's acid scaffold under
solvent-free conditions were synthesized. The antimicrobial activity was estimated by …

Green Synthesis of Electrophilic Alkenes Using a Magnesium Catalyst under Aqueous Conditions and Mechanistic Insights by Density Functional Theory

PL Kalar, K Jain, S Agrawal, S Khan… - The Journal of …, 2023 - ACS Publications
A green approach for the synthesis of electrophilic alkenes has been developed via
Knoevenagel condensation between active methylene compounds and carbonyl …

Synthesis of on resin poly (propylene imine) dendrimer and its use as organocatalyst

RKG Panicker, S Krishnapillai - Tetrahedron Letters, 2014 - Elsevier
Solid phase synthesis of poly (propylene imine) dendrimer is described. An iterative
synthesis including double Michael addition of acrylonitrile to the primary amino groups on …