Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

PEG-based thermosensitive and biodegradable hydrogels

J Shi, L Yu, J Ding - Acta biomaterialia, 2021 - Elsevier
Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room
temperature, making them easy to encapsulate the therapeutic payload or cells via simply …

Hydrogel scaffolds for differentiation of adipose-derived stem cells

Q Huang, Y Zou, MC Arno, S Chen, T Wang… - Chemical Society …, 2017 - pubs.rsc.org
Natural extracellular matrices (ECMs) have been widely used as a support for the adhesion,
migration, differentiation, and proliferation of adipose-derived stem cells (ADSCs). However …

Smart hydrogels–synthetic stimuli-responsive antitumor drug release systems

A Kasiński, M Zielińska-Pisklak, E Oledzka… - International journal …, 2020 - Taylor & Francis
Among modern drug formulations, stimuli-responsive hydrogels also called “smart
hydrogels” deserve a special attention. The basic feature of this system is the ability to …

Temperature-responsive compounds as in situ gelling biomedical materials

HJ Moon, MH Park, MK Joo, B Jeong - Chemical Society Reviews, 2012 - pubs.rsc.org
Aqueous solutions that undergo sol-to-gel transition as the temperature increases have
been extensively studied during the last decade. The material can be designed by …

Injectable and In Situ-Formable Thiolated Chitosan-Coated Liposomal Hydrogels as Curcumin Carriers for Prevention of In Vivo Breast Cancer Recurrence

R Li, Z Lin, Q Zhang, Y Zhang, Y Liu, Y Lyu… - … applied materials & …, 2020 - ACS Publications
To improve water solubility and bioavailability, curcumin (Cur) was encapsulated by
liposomes (Cur-Lip), which was further coated with thiolated chitosan (CSSH) to form …

[HTML][HTML] The contemporary role of ε-caprolactone chemistry to create advanced polymer architectures

AL Sisson, D Ekinci, A Lendlein - Polymer, 2013 - Elsevier
Abstract Poly (ε-caprolactones)(PCLs) belong to the first generation of synthetic aliphatic
polyesters. Their biodegradability motivated their extensive exploration as resorbable …

Polymeric modification and its implication in drug delivery: poly-ε-caprolactone (PCL) as a model polymer

TK Dash, VB Konkimalla - Molecular pharmaceutics, 2012 - ACS Publications
Biodegradable polymers provided the opportunity to explore beyond conventional drug
delivery and turned out to be the focus of current drug delivery. In spite of availability of …

Injectable implants for the sustained release of protein and peptide drugs

P Agarwal, ID Rupenthal - Drug discovery today, 2013 - Elsevier
Protein and peptide macromolecules have emerged as promising therapeutic agents in
recent years. However, their delivery to the target site can be challenging owing to their …