Glycemic control in the intensive care unit: a control systems perspective
Computers and automation have revolutionised quality and productivity in many industries,
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
Untangling glycaemia and mortality in critical care
Background Hyperglycaemia is associated with adverse outcomes in the intensive care unit,
and initial studies suggested outcome benefits of glycaemic control (GC). However …
and initial studies suggested outcome benefits of glycaemic control (GC). However …
Simulation of left atrial function using a multi-scale model of the cardiovascular system
During a full cardiac cycle, the left atrium successively behaves as a reservoir, a conduit and
a pump. This complex behavior makes it unrealistic to apply the time-varying elastance …
a pump. This complex behavior makes it unrealistic to apply the time-varying elastance …
3D kernel-density stochastic model for more personalized glycaemic control: development and in-silico validation
Background The challenges of glycaemic control in critically ill patients have been debated
for 20 years. While glycaemic control shows benefits inter-and intra-patient metabolic …
for 20 years. While glycaemic control shows benefits inter-and intra-patient metabolic …
[PDF][PDF] Evaluation and development of the dynamic insulin sensitivity and secretion test for numerous clinical applications
PD Docherty - 2011 - ir.canterbury.ac.nz
Given the high and increasing social, health and economic costs of type 2 diabetes, early
diagnosis and prevention are critical. Insulin sensitivity and insulin secretion are important …
diagnosis and prevention are critical. Insulin sensitivity and insulin secretion are important …
Insulin sensitivity in critically ill patients: are women more insulin resistant?
Background Glycaemic control (GC) in intensive care unit is challenging due to significant
inter-and intra-patient variability, leading to increased risk of hypoglycaemia. Recent work …
inter-and intra-patient variability, leading to increased risk of hypoglycaemia. Recent work …
A spectrum of dynamic insulin sensitivity test protocols
Background: Numerous tests have been developed to estimate insulin sensitivity (SI).
However, most of the established tests are either too expensive for widespread application …
However, most of the established tests are either too expensive for widespread application …
Estimating enhanced endogenous glucose production in intensive care unit patients with severe insulin resistance
A Yahia, Á Szlávecz, JL Knopp… - Journal of Diabetes …, 2022 - journals.sagepub.com
Background: Critically ill ICU patients frequently experience acute insulin resistance and
increased endogenous glucose production, manifesting as stress-induced hyperglycemia …
increased endogenous glucose production, manifesting as stress-induced hyperglycemia …
Risk and reward: extending stochastic glycaemic control intervals to reduce workload
Background STAR is a model-based, personalised, risk-based dosing approach for
glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly …
glycaemic control (GC) in critically ill patients. STAR provides safe, effective control to nearly …
Estimating increased EGP during stress response in critically ill patients
JJ Ormsbee, JL Knopp… - Journal of Diabetes …, 2021 - journals.sagepub.com
Background: Stress-induced hyperglycemia is frequently experienced by critically ill patients
and the use of glycemic control (GC) has been shown to improve patient outcomes. For …
and the use of glycemic control (GC) has been shown to improve patient outcomes. For …