Acinetobacter metabolism in infection and antimicrobial resistance

X Ren, LD Palmer - Infection and Immunity, 2023 - Am Soc Microbiol
Acinetobacter infections have high rates of mortality due to an increasing incidence of
infections by multidrug-resistant (MDR) and extensively-drug-resistant (XDR) strains …

Bacterial acquisition of host fatty acids has far-reaching implications on virulence

JK Waters, BA Eijkelkamp - Microbiology and Molecular Biology …, 2024 - journals.asm.org
The lipid homeostasis pathways of bacterial pathogens have been studied comprehensively
for their biochemical functionality. However, new and refined technologies have supported …

Shigella flexneri Adapts to Niche-Specific Stresses through Modifications in Cell Envelope Composition and Decoration

A Ascari, JK Waters, R Morona… - ACS Infectious …, 2023 - ACS Publications
Shigella flexneri is the primary causative agent of worldwide shigellosis. As the pathogen
transverses the distinct niches of the gastrointestinal tract it necessitates dynamic adaptation …

[HTML][HTML] Characterizing the role of phosphatidylglycerol-phosphate phosphatases in Acinetobacter baumannii cell envelope biogenesis and antibiotic resistance

M Zang, A Ascari, FG Adams, S Alquethamy… - The Cell Surface, 2023 - Elsevier
The dissemination of multi-drug resistant Acinetobacter baumannii threatens global
healthcare systems and necessitates the development of novel therapeutic options. The …

The impact of omega-3 fatty acids on the evolution of Acinetobacter baumannii drug resistance

M Zang, FG Adams, KA Hassan… - Microbiology …, 2021 - Am Soc Microbiol
The bacterial pathogen Acinetobacter baumannii has emerged as an urgent threat to health
care systems. The prevalence of multidrug resistance in this critical human pathogen is …

The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance

SF Alquethamy, FG Adams, R Maharjan… - Applied and …, 2021 - Am Soc Microbiol
Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, in
soil, and as commensals of the human skin. The successful inhabitation of Acinetobacter …

Fatty Acid Uptake in Klebsiella pneumoniae and the Landscape of Its Infectious Niches

E Haracic, JK Waters, T Nguyen Thi Nguyen… - ACS Infectious …, 2024 - ACS Publications
Klebsiella pneumoniae is consistently ranked among the most problematic multidrug-
resistant bacterial pathogens in healthcare systems. Developing novel treatments requires a …

Shigella flexneri remodeling and consumption of host lipids during infection

A Ascari, S Frölich, M Zang, ENH Tran… - Journal of …, 2023 - Am Soc Microbiol
Shigella flexneri is a major cause of bacillary dysentery in the developing world,
predominantly affecting the pediatric age group, with malnutrition being a common co …

Lipidome of Acinetobacter baumannii antibiotic persister cells

D Vergoz, A Schaumann, I Schmitz, C Afonso… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Persister cells constitute a bacterial subpopulation able to survive to high concentrations of
antibiotics. This phenotype is temporary and reversible, and thus could be involved in the …

Lipidomic analyses reveal distinctive variations in homeoviscous adaptation among clinical strains of Acinetobacter baumannii, providing insights from an …

C Dessenne, B Ménart, S Acket, G Dewulf… - Microbiology …, 2024 - journals.asm.org
Acinetobacter baumannii is known for its antibiotic resistance and is increasingly found
outside of healthcare settings. To survive colder temperatures, bacteria, including A …