Review of Molecular Technologies for Investigating Canine Cancer

A Kehl, H Aupperle-Lellbach, S de Brot… - Animals, 2024 - mdpi.com
Simple Summary Genetic molecular testing is starting to become part of standard clinical
practice for dogs with cancer as it can assist veterinarians with diagnosis, provide …

Tumour incidence in dogs in Germany: a retrospective analysis of 109,616 histopathological diagnoses (2014–2019)

H Aupperle-Lellbach, JM Grassinger, A Floren… - Journal of Comparative …, 2022 - Elsevier
Characterization of a tumour entity is based on the precise histopathological diagnosis
taking into account the signalment of the diseased animal. The present study is a …

Clinical Use of Molecular Biomarkers in Canine and Feline Oncology: Current and Future

H Aupperle-Lellbach, A Kehl, S de Brot… - Veterinary …, 2024 - mdpi.com
Simple Summary Molecular biomarkers in cancer are measurable genomic alterations that
can indicate the risk of developing neoplasia, the presence of neoplastic cells, patient …

Immunohistochemical and molecular genetic analysis of canine digital mast cell tumours

D Conrad, A Kehl, T Müller, R Klopfleisch… - Animals, 2023 - mdpi.com
Simple Summary In veterinary medicine, methods such as histological grading,
immunohistochemistry and mutation analysis of the c-kit gene are tools to assess the …

Cross-Species Comparison of the Pan-RAF Inhibitor LY3009120's Anti-Tumor Effects in Equine, Canine, and Human Malignant Melanoma Cell Lines

Y Gao, EM Packeiser, S Wendt, A Sekora… - Genes, 2024 - mdpi.com
Malignant melanomas (MMs) are the abnormal proliferation of melanocytes and are one of
the lethal skin cancers in humans, equines, and canines. Accordingly, MMs in companion …

Advances in understanding spontaneously occurring melanoma in animals

KL Blacklock, L van der Weyden - Veterinary Sciences, 2023 - mdpi.com
Melanoma is a tumour that arises from the uncontrolled proliferation of melanocytes
(pigment-producing cells) found in the skin (cutaneous melanoma and digital melanoma) …

[HTML][HTML] Exploring the Epidemiology of Melanocytic Tumors in Canine and Feline Populations: A Comprehensive Analysis of Diagnostic Records from a Single …

A Lo Giudice, I Porcellato, G Giglia, M Sforna… - Veterinary …, 2024 - mdpi.com
Simple Summary Melanocytic tumors (MTs) are more prevalent in dogs than in cats. In dogs,
they are the most frequent malignancy of the oral cavity, whereas in cats, ocular melanomas …

[PDF][PDF] Immunohistochemical and Molecular Genetic Analysis of Canine Digital Mast Cell Tumours. Animals 2023, 13, 1694

D Conrad, A Kehl, T Müller, R Klopfleisch… - 2023 - core.ac.uk
Grading, immunohistochemistry and c-kit mutation status are criteria for assessing the
prognosis and therapeutic options of canine cutaneous mast cell tumours (MCTs). As a …

KITLG copy number germline variations in schnauzer breeds and their relevance in digital squamous cell carcinoma in black giant schnauzers

H Aupperle-Lellbach, D Heidrich, A Kehl, D Conrad… - Veterinary …, 2023 - mdpi.com
Simple Summary It is well known that dark-coated dogs, especially schnauzers, have a
predisposition for digital squamous cell carcinoma (dSCC). Molecular genetic studies by …

Comparação da avaliação da mutação V595E do gene BRAF na urina de cães com carcinoma urotelial de bexiga pelos métodos de PCR em tempo real e digital

TA Santos - 2024 - repositorio.unesp.br
O câncer de bexiga é uma neoplasia de bexiga importante em homens e animais, devido à
sua alta incidência. O carcinoma urotelial de bexiga (CUB) é considerado a neoplasia do …