Non-invasive drug delivery across the blood–brain barrier: a prospective analysis
SK Niazi - Pharmaceutics, 2023 - mdpi.com
Non-invasive drug delivery across the blood–brain barrier (BBB) represents a significant
advancement in treating neurological diseases. The BBB is a tightly packed layer of …
advancement in treating neurological diseases. The BBB is a tightly packed layer of …
Niosomes for nose-to-brain delivery: a non-invasive versatile carrier system for drug delivery in neurodegenerative diseases
AR Al Jayoush, HAFM Hassan, H Asiri, M Jafar… - Journal of Drug Delivery …, 2023 - Elsevier
Neurodegenerative diseases (NDDs) significantly contribute to morbidity and mortality
worldwide. The suboptimal effect of currently used therapeutic approaches administered via …
worldwide. The suboptimal effect of currently used therapeutic approaches administered via …
[HTML][HTML] Access to the CNS: Strategies to overcome the BBB
B Sánchez-Dengra, I González-Álvarez… - International Journal of …, 2023 - Elsevier
The blood–brain barrier (BBB) limits the access of substances to the central nervous system
(CNS) which hinders the treatment of pathologies affecting the brain and the spinal cord …
(CNS) which hinders the treatment of pathologies affecting the brain and the spinal cord …
Challenges and Future Perspectives in Modeling Neurodegenerative Diseases Using Organ‐on‐a‐Chip Technology
Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …
a significant global health challenge as well as a high socioeconomic burden. With aging …
Neuroprotective peptides and new strategies for ischemic stroke drug discoveries
LV Dergunova, IB Filippenkov, SA Limborska… - Genes, 2023 - mdpi.com
Ischemic stroke continues to be one of the leading causes of death and disability in the adult
population worldwide. The currently used pharmacological methods for the treatment of …
population worldwide. The currently used pharmacological methods for the treatment of …
Advancements in the Application of Nanomedicine in Alzheimer's Disease: A Therapeutic Perspective
Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects most
people worldwide. AD is a complex central nervous system disorder. Several drugs have …
people worldwide. AD is a complex central nervous system disorder. Several drugs have …
Advances in nanotherapeutic strategies for Huntington's disease: Design, delivery, and neuroprotective mechanisms
Huntington's Disease (HD) is a severe neurodegenerative disorder lacking effective
diagnostic and treatment options. However, there is increasing interest in the potential of …
diagnostic and treatment options. However, there is increasing interest in the potential of …
Towards Novel Biomimetic In Vitro Models of the Blood–Brain Barrier for Drug Permeability Evaluation
Current available animal and in vitro cell-based models for studying brain-related
pathologies and drug evaluation face several limitations since they are unable to reproduce …
pathologies and drug evaluation face several limitations since they are unable to reproduce …
Nanomaterial-Based Strategies for Attenuating T-Cell-Mediated Immunodepression in Stroke Patients: Advancing Research Perspectives
Y Wang, C Liu, Y Ren, J Song, K Fan… - International Journal …, 2024 - Taylor & Francis
This review article discusses the potential of nanomaterials in targeted therapy and
immunomodulation for stroke-induced immunosuppression. Although nanomaterials have …
immunomodulation for stroke-induced immunosuppression. Although nanomaterials have …
Progress of nanoparticle drug delivery system for the treatment of glioma
G Lai, H Wu, K Yang, K Hu, Y Zhou, X Chen… - … in Bioengineering and …, 2024 - frontiersin.org
Gliomas are typical malignant brain tumours affecting a wide population worldwide.
Operation, as the common treatment for gliomas, is always accompanied by postoperative …
Operation, as the common treatment for gliomas, is always accompanied by postoperative …