Roles for chemokines in liver disease

F Marra, F Tacke - Gastroenterology, 2014 - Elsevier
Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …

HIV-hepatitis B virus coinfection: epidemiology, pathogenesis, and treatment

KP Singh, M Crane, J Audsley, A Avihingsanon… - Aids, 2017 - journals.lww.com
HIV infection has a significant impact on the natural history of chronic hepatitis B virus (HBV)
infection, with increased levels of HBV DNA, accelerated progression of liver disease and …

[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases

JH Ellwanger, B Kulmann-Leal, V de Lima Kaminski… - Virus research, 2020 - Elsevier
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …

How palmitoylation affects trafficking and signaling of membrane receptors

M Jansen, B Beaumelle - Biology of the Cell, 2022 - Wiley Online Library
S‐acylation (or palmitoylation) is a reversible post‐translational modification (PTM) that
modulates protein activity, signalization and trafficking. Palmitoylation was found to …

[HTML][HTML] Cytoplasm-translocated Ku70/80 complex sensing of HBV DNA induces hepatitis-associated chemokine secretion

Y Li, Y Wu, X Zheng, J Cong, Y Liu, J Li, R Sun… - Frontiers in …, 2016 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a serious disease, mainly due to its severe
pathological consequences, which are difficult to cure using current therapies. When the …

Host–virus interaction and viral evasion

ST Strumillo, D Kartavykh… - Cell Biology …, 2021 - Wiley Online Library
With each infectious pandemic or outbreak, the medical community feels the need to revisit
basic concepts of immunology to understand and overcome the difficult times brought about …

Changes in genital tract immune cell populations after initiation of intrauterine contraception

SL Achilles, MD Creinin, KA Stoner, BA Chen… - American journal of …, 2014 - Elsevier
Objective The primary target cells for the human immunodeficiency virus (HIV) infection in
the genital tract are CD4 T cells that express CCR5 on the surface. Alterations in genital tract …

[HTML][HTML] Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus

C Méndez, CL Ahlenstiel, AD Kelleher - World Journal of Virology, 2015 - ncbi.nlm.nih.gov
While human immunodeficiency virus 1 (HIV-1) infection is controlled through continuous,
life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is …

Delivery of toll-like receptor 3 ligand poly (I: C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect …

Y Du, X Yang, J Li, V Sokolova, S Zou, M Han, H Yan… - Acta Biomaterialia, 2021 - Elsevier
Hepatitis B virus (HBV) is a global health issue, but currently available anti-HBV drugs have
limited success. Previously, introduction of the Toll-like receptor (TLR)-3 ligand poly (I: C) to …

Impact of genetic variations in CC chemokine receptors and ligands on infectious diseases

T Qidwai, MY Khan - Human immunology, 2016 - Elsevier
Chemokine receptors and ligands are crucial for extensive immune response against
infectious diseases such as malaria, leishmaniasis, HIV and tuberculosis and a wide variety …