Roles for chemokines in liver disease
F Marra, F Tacke - Gastroenterology, 2014 - Elsevier
Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …
HIV-hepatitis B virus coinfection: epidemiology, pathogenesis, and treatment
HIV infection has a significant impact on the natural history of chronic hepatitis B virus (HBV)
infection, with increased levels of HBV DNA, accelerated progression of liver disease and …
infection, with increased levels of HBV DNA, accelerated progression of liver disease and …
[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …
infectious diseases as well as their clinical manifestations. These interactions mediate both …
How palmitoylation affects trafficking and signaling of membrane receptors
M Jansen, B Beaumelle - Biology of the Cell, 2022 - Wiley Online Library
S‐acylation (or palmitoylation) is a reversible post‐translational modification (PTM) that
modulates protein activity, signalization and trafficking. Palmitoylation was found to …
modulates protein activity, signalization and trafficking. Palmitoylation was found to …
[HTML][HTML] Cytoplasm-translocated Ku70/80 complex sensing of HBV DNA induces hepatitis-associated chemokine secretion
Y Li, Y Wu, X Zheng, J Cong, Y Liu, J Li, R Sun… - Frontiers in …, 2016 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a serious disease, mainly due to its severe
pathological consequences, which are difficult to cure using current therapies. When the …
pathological consequences, which are difficult to cure using current therapies. When the …
Host–virus interaction and viral evasion
ST Strumillo, D Kartavykh… - Cell Biology …, 2021 - Wiley Online Library
With each infectious pandemic or outbreak, the medical community feels the need to revisit
basic concepts of immunology to understand and overcome the difficult times brought about …
basic concepts of immunology to understand and overcome the difficult times brought about …
Changes in genital tract immune cell populations after initiation of intrauterine contraception
Objective The primary target cells for the human immunodeficiency virus (HIV) infection in
the genital tract are CD4 T cells that express CCR5 on the surface. Alterations in genital tract …
the genital tract are CD4 T cells that express CCR5 on the surface. Alterations in genital tract …
[HTML][HTML] Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus
C Méndez, CL Ahlenstiel, AD Kelleher - World Journal of Virology, 2015 - ncbi.nlm.nih.gov
While human immunodeficiency virus 1 (HIV-1) infection is controlled through continuous,
life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is …
life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is …
Delivery of toll-like receptor 3 ligand poly (I: C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect …
Y Du, X Yang, J Li, V Sokolova, S Zou, M Han, H Yan… - Acta Biomaterialia, 2021 - Elsevier
Hepatitis B virus (HBV) is a global health issue, but currently available anti-HBV drugs have
limited success. Previously, introduction of the Toll-like receptor (TLR)-3 ligand poly (I: C) to …
limited success. Previously, introduction of the Toll-like receptor (TLR)-3 ligand poly (I: C) to …
Impact of genetic variations in CC chemokine receptors and ligands on infectious diseases
Chemokine receptors and ligands are crucial for extensive immune response against
infectious diseases such as malaria, leishmaniasis, HIV and tuberculosis and a wide variety …
infectious diseases such as malaria, leishmaniasis, HIV and tuberculosis and a wide variety …