Genetic load: genomic estimates and applications in non-model animals
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
Prevalence and adaptive impact of introgression
NB Edelman, J Mallet - Annual Review of Genetics, 2021 - annualreviews.org
Alleles that introgress between species can influence the evolutionary and ecological fate of
species exposed to novel environments. Hybrid offspring of different species are often unfit …
species exposed to novel environments. Hybrid offspring of different species are often unfit …
The crucial role of genome-wide genetic variation in conservation
M Kardos, EE Armstrong… - Proceedings of the …, 2021 - National Acad Sciences
The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …
biodiversity. Several recent genomic and simulation-based studies have argued that the …
Genetic diversity loss in the Anthropocene
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …
increasing extinction risk and losses of species' genetic diversity. Although preserving …
Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species
About 50 y ago, Crow and Kimura [An Introduction to Population Genetics Theory (1970)]
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …
The inflated significance of neutral genetic diversity in conservation genetics
JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …
Deleterious variation in natural populations and implications for conservation genetics
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …
that many organisms face ongoing threats of extinction, there is interest in elucidating the …
The critically endangered vaquita is not doomed to extinction by inbreeding depression
In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …
Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …
populations through gene flow-is valuable in wildlife conservation. Empirically validated …
Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers
Increasing habitat fragmentation leads to wild populations becoming small, isolated, and
threatened by inbreeding depression. However, small populations may be able to purge …
threatened by inbreeding depression. However, small populations may be able to purge …