During embryonic development, a simple ball of cells re-shapes itself into the elaborate
body plan of an animal. This requires dramatic cell shape changes and cell movements …

Gastrulation is the period of development when the three germ layers, mesoderm, endoderm
and ectoderm, are not only formed, but also shaped into a rudimentary body plan. An …

An extracellular matrix of Fibronectin adheres the neural tube to the two flanking columns of
paraxial mesoderm and is required for normal vertebrate development. Here, we find that …

The underlying mechanisms of appendage regeneration remain largely unknown and
uncovering these mechanisms in capable organisms has far‐reaching implications for …

Primary neurulation is the process by which the neural tube, the central nervous system
precursor, is formed from the neural plate. Incomplete neural tube closure occurs frequently …

Neural tube defects (NTDs) are among the most devastating and common congenital
anomalies worldwide, and the ability to model these conditions in vivo is essential for …

The internalization of the central nervous system, termed neurulation in vertebrates, is a
critical step in embryogenesis. Open questions remain regarding how force propels …

Polycomb repressive complex 2 (PRC2) mediates histone H3K27me3 methylation and the
stable transcriptional repression of a number of gene expression programs involved in the …

The internalization of multi-cellular tissues is a key morphogenetic process during animal
development and organ formation. A good example of this is the initial stages of vertebrate …

Classical cadherin gene family relies on calcium ions in playing an important role in
adhesion between cells. However, comprehensive studies to identify classical cadherin …