Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

J Xie, Y Wang, W Choi, P Jangili, Y Ge, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Recent advances in nanomaterial‐assisted combinational sonodynamic cancer therapy

S Liang, X Deng, P Ma, Z Cheng, J Lin - Advanced Materials, 2020 - Wiley Online Library
Ultrasound (US)‐triggered sonodynamic therapy (SDT), as a promising noninvasive
therapeutic modality, has received ever‐increasing attention in recent years. Its specialized …

Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT

L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …

De novo design of reversibly PH-switchable NIR-II aggregation-induced emission luminogens for efficient phototheranostics of patient-derived tumor xenografts

P Xiao, W Xie, J Zhang, Q Wu, Z Shen… - Journal of the …, 2022 - ACS Publications
Phototheranostics has received sustained attention due to its great potential in
revolutionizing conventional strategies of cancer treatment. However, trapped by the …

Supramolecular photosensitizers rejuvenate photodynamic therapy

X Li, S Lee, J Yoon - Chemical Society Reviews, 2018 - pubs.rsc.org
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT)
has become a clinically promising approach for the treatment of a wide range of cancers and …

All-in-one theranostic nanoagent with enhanced reactive oxygen species generation and modulating tumor microenvironment ability for effective tumor eradication

Y Liu, W Zhen, L Jin, S Zhang, G Sun, T Zhang, X Xu… - ACS …, 2018 - ACS Publications
Despite regulation of the reactive oxygen species (ROS) level is an intelligent strategy for
cancer therapy, the therapeutic effects of ROS-mediated therapy (including photodynamic …

Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives

QL Guo, XL Dai, MY Yin, HW Cheng, HS Qian… - Military Medical …, 2022 - Springer
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is
associated with poor prognosis. Its characteristics of being highly invasive and undergoing …

Self‐assembled peptide‐and protein‐based nanomaterials for antitumor photodynamic and photothermal therapy

M Abbas, Q Zou, S Li, X Yan - Advanced materials, 2017 - Wiley Online Library
Tremendous interest in self‐assembly of peptides and proteins towards functional
nanomaterials has been inspired by naturally evolving self‐assembly in biological …

[HTML][HTML] Strategies for preparing albumin-based nanoparticles for multifunctional bioimaging and drug delivery

FF An, XH Zhang - Theranostics, 2017 - ncbi.nlm.nih.gov
Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic
ingredient of human blood without immunogenicity and encouraged by its successful clinical …

Bioinspired hybrid protein oxygen nanocarrier amplified photodynamic therapy for eliciting anti-tumor immunity and abscopal effect

Z Chen, L Liu, R Liang, Z Luo, H He, Z Wu, H Tian… - Acs Nano, 2018 - ACS Publications
An ideal cancer therapeutic strategy is expected to possess potent ability to not only ablate
primary tumors but also prevent distance metastasis and relapse. In this study, human serum …