EGFR is a prototypical receptor tyrosine kinase that is overexpressed in multiple cancers
including head and neck squamous cell carcinoma (HNSCC). The standard of care for …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type,
has often an aggressive course and is poorly responsive to current therapeutic approaches …

The EGFR pathway plays a critical role in head and neck squamous cell carcinoma
(HNSCC). Targeted therapies against the EGFR are utilized as a treatment for HNSCCC …

Metastasis is a critical step in the process of carcinogenesis and a vast majority of cancer-
related mortalities result from metastatic disease that is resistant to current therapies. Cell …

Epidermal growth factor receptor (EGFR) is a pro-tumorigenic receptor tyrosine kinase that
facilitates growth for cancer cells that overexpress the receptor. Monoclonal anti-EGFR …

The epidermal growth factor receptor (EGFR) is a key player in the normal tissue physiology
and the pathology of cancer. Therapeutic approaches have now been developed to target …

Simple Summary The ecosystem that surrounds a tumour, the microenvironment, has a
huge impact on the spread of cancer, but its exact role in the molecular mechanism of …

Most Phase II and III clinical trials in head and neck cancer (HNC) combine two or more
treatment modalities, which are based, in part, on knowledge of the molecular mechanisms …

Thesis presented to the Faculty of medicine and health sciences for the obtention of Master
Science degree (M. Sc.) in Radiation Sciences and Biomedical Imaging, Faculty of medicine …