The focus of the “2014 AHA/ACC Guideline for the Management of Patients With Valvular
Heart Disease” 9, 10 (2014 VHD guideline) was the diagnosis and management of adult …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Background Valvular heart disease (VHD) is expected to become more common as the
population ages. However, current estimates of its natural history and prevalence are based …

Prosthetic heart valve (PHV) dysfunction is rare but potentially life-threatening. Although
often challenging, establishing the exact cause of PHV dysfunction is essential to determine …

Mechanical valves used for aortic valve replacement (AVR) continue to be associated with
bleeding risks because of anticoagulation therapy, while bioprosthetic valves are at risk of …

Background The introduction of transcatheter aortic valve replacement mandates attention to
outcomes after surgical aortic valve replacement (SAVR) in low-risk, intermediate-risk, and …

Aims The objective was to investigate the long-term all-cause mortality in patients aged 50–
69 years after aortic valve replacement (AVR) with bioprosthetic or mechanical valves …

Objective Substantial controversy surrounds the choice between a mechanical versus
bioprosthetic prosthesis for aortic valve replacement (AVR), based on age. This study aims …

Importance There is a need to describe contemporary outcomes of surgical aortic valve
replacement (AVR) as the population ages and transcatheter options emerge. Objective To …