[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Vulnerable plaque, characteristics, detection, and potential therapies

A Hafiane - Journal of cardiovascular development and disease, 2019 - mdpi.com
Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite
current therapeutic developments, there is an unmet necessity in the prevention of …

Highly bright AIE nanoparticles by regulating the substituent of rhodanine for precise early detection of atherosclerosis and drug screening

K Wang, H Gao, Y Zhang, H Yan, J Si, X Mi… - Advanced …, 2022 - Wiley Online Library
Fluorescent probes capable of precise detection of atherosclerosis (AS) at an early stage
and fast assessment of anti‐AS drugs in animal level are particularly valuable. Herein, a …

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation

DI Cho, MJ Ahn, HH Cho, M Cho, JH Jun… - … & molecular medicine, 2023 - nature.com
Atherosclerosis, the leading cause of death, is a vascular disease of chronic inflammation.
We recently showed that angiopoietin-like 4 (ANGPTL4) promotes cardiac repair by …

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …

Atorvastatin inhibits inflammatory response, attenuates lipid deposition, and improves the stability of vulnerable atherosclerotic plaques by modulating autophagy

S Peng, LW Xu, XY Che, QQ Xiao, J Pu… - Frontiers in …, 2018 - frontiersin.org
Atherosclerosis is a chronic disease comprising intima malfunction and arterial
inflammation. Recent studies have demonstrated that autophagy could inhibit inflammatory …

Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering

C Härdtner, J Kornemann, K Krebs, CA Ehlert… - Basic Research in …, 2020 - Springer
Statins induce plaque regression characterized by reduced macrophage content in humans,
but the underlying mechanisms remain speculative. Studying the translational APOE* 3 …

A randomized trial of direct pulp capping in primary molars using MTA compared to 3Mixtatin: a novel pulp capping biomaterial

N Asl Aminabadi, S Satrab, E Najafpour… - … journal of paediatric …, 2016 - Wiley Online Library
Objective This study aimed to examine the efficacy of 3Mixtatin (a combination of simvastatin
and 3Mix antibiotic) as a novel pulp capping biomaterial in DPC of human primary molars …

Protective effects of quercetin and taraxasterol against H2O2‑induced human umbilical vein endothelial cell injury in vitro

D Yang, X Liu, M Liu, H Chi… - Experimental and …, 2015 - spandidos-publications.com
Due to the association between inflammation and endothelial dysfunction in atherosclerosis,
the blockage of the inflammatory process that occurs on the endothelial cells may be a …

Ginkgo Biloba Leaf Extract Attenuates Atherosclerosis in Streptozotocin‐Induced Diabetic ApoE‐/‐Mice by Inhibiting Endoplasmic Reticulum Stress via Restoration of …

J Tian, MS Popal, Y Liu, R Gao, S Lyu… - Oxidative Medicine …, 2019 - Wiley Online Library
Background. There is a crosstalk between endoplasmic reticulum stress (ERS) and
autophagy, and autophagy could attenuate endoplasmic reticulum stress‐mediated …