Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine

J Zhai, C Fong, N Tran, CJ Drummond - ACS nano, 2019 - ACS Publications
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …

Monoolein: a magic lipid?

CV Kulkarni, W Wachter, G Iglesias-Salto… - Physical Chemistry …, 2011 - pubs.rsc.org
During the last few years, there has been an extraordinary increase in publications
describing the manifold applications of monoolein, one of the most important lipids in the …

Correlating the structure and gene silencing activity of oligonucleotide-loaded lipid nanoparticles using small-angle X-ray scattering

M Hammel, Y Fan, A Sarode, AE Byrnes, N Zang… - ACS …, 2023 - ACS Publications
With three FDA-approved products, lipid nanoparticles (LNPs) are under intensive
development for delivering wide-ranging nucleic acid therapeutics. A significant challenge …

Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents

A Angelova, VM Garamus, B Angelov, Z Tian… - Advances in colloid and …, 2017 - Elsevier
The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …

Advances in drug delivery and medical imaging using colloidal lyotropic liquid crystalline dispersions

X Mulet, BJ Boyd, CJ Drummond - Journal of colloid and interface science, 2013 - Elsevier
The overarching goal of this feature article is to review the recent developments in the field
of drug delivery specifically involving colloidal lyotropic liquid crystalline dispersions. The …

Lyotropic liquid crystal engineering moving beyond binary compositional space–ordered nanostructured amphiphile self-assembly materials by design

L van't Hag, SL Gras, CE Conn… - Chemical society …, 2017 - pubs.rsc.org
Ordered amphiphile self-assembly materials with a tunable three-dimensional (3D)
nanostructure are of fundamental interest, and crucial for progressing several biological and …

Self-assembled multicompartment liquid crystalline lipid carriers for protein, peptide, and nucleic acid drug delivery

A Angelova, B Angelov, R Mutafchieva… - Accounts of chemical …, 2011 - ACS Publications
Lipids and lipopolymers self-assembled into biocompatible nano-and mesostructured
functional materials offer many potential applications in medicine and diagnostics. In this …

Composition-switchable liquid crystalline nanostructures as green formulations of curcumin and fish oil

M Rakotoarisoa, B Angelov, S Espinoza… - ACS Sustainable …, 2021 - ACS Publications
Green compositions and processes for fabrication of dual-and multiloaded nanocarriers with
an antioxidant functionality and neuroprotective, cardioprotective, antiviral, and …

Rapidly dissolving microneedles for the delivery of cubosome-like liquid crystalline nanoparticles with sustained release of rapamycin

A Ramalheiro, JL Paris, BFB Silva, LR Pires - International Journal of …, 2020 - Elsevier
In this study, we developed a system for the transdermal delivery and controlled release of
the hydrophobic immunosuppressive drug rapamycin, foreseeing an application in psoriasis …

From molecular to nanotechnology strategies for delivery of neurotrophins: emphasis on brain-derived neurotrophic factor (BDNF)

C Géral, A Angelova, S Lesieur - Pharmaceutics, 2013 - mdpi.com
Neurodegenerative diseases represent a major public health problem, but beneficial clinical
treatment with neurotrophic factors has not been established yet. The therapeutic use of …